Zhang Xiaomei, Liang Yanyan, Feng Wanyu, Su Xuewen, Zhu Hua
Department of Pediatrics, Inner Mongolia Autonomous Region People's Hospital, Hohhot, Inner Mongolia 010017, P.R. China.
Exp Ther Med. 2016 Aug;12(2):1220-1224. doi: 10.3892/etm.2016.3393. Epub 2016 May 26.
The epidemiologic features of Kawasaki disease (KD) in the Inner Mongolia Autonomous Region of China has not been previously determined, to the best of our knowledge. Therefore, the aim of the present study was to investigate the epidemiology of KD in Inner Mongolia. Clinical data from 518 patients treated for KD in Inner Mongolia between January 2001 and December 2013 were analyzed. The results indicated that the mean annual incidence rate was 3.55±2.96 per 100,000 children under the age of 5 years between 2001 and 2013. The age at diagnosis ranged between 49 days and 14 years, while the disease occurred more frequently in the spring and summer. In addition, the incidence of coronary artery lesion (CAL) was reported to be 40.2% in the present survey. KD patients in the Han Chinese ethnic group were more likely to be complicated by CAL, whereas patients with incidence of KD in July were less likely to be complicated by CAL. In conclusion, the incidence of KD was observed to be increasing in Inner Mongolia, while the ethnic group and month of onset may be associated with the incidence of CAL in KD patients.
据我们所知,中国内蒙古自治区川崎病(KD)的流行病学特征此前尚未确定。因此,本研究的目的是调查内蒙古地区KD的流行病学情况。对2001年1月至2013年12月期间在内蒙古接受KD治疗的518例患者的临床资料进行了分析。结果表明,2001年至2013年期间,5岁以下儿童的年平均发病率为每10万人3.55±2.96例。诊断年龄在49天至14岁之间,该疾病在春季和夏季更为常见。此外,本次调查中冠状动脉病变(CAL)的发生率据报道为40.2%。汉族KD患者更易并发CAL,而7月发病的KD患者并发CAL的可能性较小。总之,观察到内蒙古地区KD的发病率在上升,而种族和发病月份可能与KD患者CAL的发生率有关。