Li Zhuoying, Han Dong, Jiang Jie, Chen Jia, Tian Lang, Yang Zuocheng
Department of Pediatrics, The Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, China.
Dis Markers. 2017;2017:2960502. doi: 10.1155/2017/2960502. Epub 2017 Apr 23.
Kawasaki disease (KD) is an acute systemic vasculitis complicated by development of coronary artery lesions. PECAM-1 is a kind of cell adhesion molecule, which plays an important role in coronary artery disease. The relationship between PECAM-1 gene polymorphisms and their susceptibility to Kawasaki diseases (KD) is still unclear. In our study, we examined the PECAM-1 gene polymorphisms in 44 KD patients and 59 healthy children and revealed the correlation of PECAM-1 gene polymorphisms in KD children with and without coronary artery lesions (CAL).
川崎病（KD）是一种急性全身性血管炎，可并发冠状动脉病变。血小板内皮细胞黏附分子-1（PECAM-1）是一种细胞黏附分子，在冠状动脉疾病中起重要作用。PECAM-1基因多态性与其对川崎病（KD）的易感性之间的关系仍不清楚。在我们的研究中，我们检测了44例KD患者和59例健康儿童的PECAM-1基因多态性，并揭示了KD患儿有无冠状动脉病变（CAL）时PECAM-1基因多态性的相关性。
