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心血管反射与长期低剂量汞蒸气暴露。

Cardiovascular reflexes and low long-term exposure to mercury vapour.

作者信息

Piikivi L

机构信息

Oulu Regional Institute of Occupational Health, Division of Occupational Health, Finland.

出版信息

Int Arch Occup Environ Health. 1989;61(6):391-5. doi: 10.1007/BF00381030.

Abstract

Subjective symptoms related to autonomic dysfunction and quantitative non invasive tests measuring both sympathetic and parasympathetic functions of the autonomic nervous system were studied among a group of 41 chlorine-alkali workers with low long-term exposure to mercury (Hg degree) vapour and their matched referents. The test battery included measurements of pulse rate variation in normal and deep breathing, in the Valsalva manoeuvre and in vertical tilt as well as blood pressure responses during standing and isometric work. The exposure time had been 16 years on average, and the mean exposure to Hg vapour was estimated to have been about 30 micrograms/m3 of air. Only a tendency for a subtle reduction of cardiovascular reflex responses and a slight increase of subjective symptoms were seen in the exposed group, but no significant autonomic dysfunction was associated with the low level of exposure.

摘要

在一组41名长期低剂量接触汞(Hg度)蒸气的氯碱工人及其匹配的对照者中,研究了与自主神经功能障碍相关的主观症状以及测量自主神经系统交感和副交感神经功能的定量非侵入性测试。测试项目包括测量正常呼吸、深呼吸、瓦尔萨尔瓦动作和垂直倾斜时的脉搏率变化,以及站立和等长运动时的血压反应。平均接触时间为16年,估计汞蒸气的平均接触量约为30微克/立方米空气。在暴露组中,仅观察到心血管反射反应略有降低和主观症状略有增加的趋势,但低水平暴露与明显的自主神经功能障碍无关。

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