Langerhorst C T, van den Berg T J, Greve E L
Department of Ophthalmology, University of Amsterdam, the Netherlands.
Int Ophthalmol. 1989 Jan;13(1-2):31-5. doi: 10.1007/BF02028634.
Ten normal controls, ten ocular hypertensive patients, ten high tension, 12 medium tension and nine low tension glaucoma patients were studied prospectively by means of automated static perimetry. Multiple double threshold measurements were obtained during at most three years. A computer algorithm estimated for each visual field the Individual General Sensitivity IGS, in which local defects do not contribute. Thus we were able to estimate pure general reduction of sensitivity by comparing the IGS to age-corrected normal reference values. No significant difference in mean general reduction of sensitivity was found between the glaucoma patients and the normal group. Patients with local defects in one field half only also showed IGS values not different from normals. Our findings indicate that the impression of 'general' sensitivity loss may be caused by the presence of multiple local defects, and is not a phenomenon in itself.
对10名正常对照者、10名高眼压患者、10名高血压患者、12名中度眼压青光眼患者和9名低眼压青光眼患者进行了前瞻性自动静态视野检查研究。在最多三年的时间里进行了多次双阈值测量。一种计算机算法为每个视野估计个体总体敏感度（IGS），其中局部缺损不产生影响。因此，通过将IGS与年龄校正后的正常参考值进行比较，我们能够估计敏感度的单纯总体降低情况。青光眼患者与正常组之间在平均总体敏感度降低方面未发现显著差异。仅在一个半视野有局部缺损的患者其IGS值也与正常人无差异。我们的研究结果表明，“总体”敏感度丧失的印象可能是由多个局部缺损的存在所导致，而并非其本身就是一种现象。
