Edwards W H, Edwards W H, Jenkins J M, Mulherin J L
Department of Surgery, St. Thomas Hospital, Nashville, TN.
J Cardiovasc Surg (Torino). 1989 May-Jun;30(3):424-9.
Carotid artery reconstruction surgery for atherosclerotic lesions of the extracranial cerebral circulation has become the most common peripheral vascular operation. A better understanding of the indications for operative intervention, enhanced monitoring during surgery, and more precise management of intraoperative anesthesia have all decreased the risks associated with internal carotid endarterectomy (ICA). In an effort to evaluate the safety and efficacy of extracranial carotid reconstructive surgery, we reviewed 3028 operations performed in 2198 patients during the past decade (1977-1986). Operation was recommended because of hemispheric symptoms in 59% of cases. Fourteen percent were advised to have endarterectomy because of an asymptomatic, significant ICA stenosis. Postoperative hemiparesis occurred in 24 patients (1.1%) and was associated with thrombosis at the operative site in 18 patients. Antiplatelet drugs utilized during the last four years were effective in preventing thrombosis at the operative site. Operative mortality during the decade was 1.2%. Follow-up has ranged from one to. 104 months with 86% of the patients alive and 87% symptom free.
用于颅外脑循环动脉粥样硬化病变的颈动脉重建手术已成为最常见的外周血管手术。对手术干预指征的更好理解、手术期间加强监测以及术中麻醉的更精确管理,都降低了与颈动脉内膜切除术(ICA)相关的风险。为了评估颅外颈动脉重建手术的安全性和有效性,我们回顾了过去十年(1977 - 1986年)在2198例患者中进行的3028例手术。59%的病例因半球症状而建议进行手术。14%的患者因无症状的严重ICA狭窄而被建议进行内膜切除术。术后偏瘫发生在24例患者中(1.1%),其中18例与手术部位血栓形成有关。过去四年中使用的抗血小板药物在预防手术部位血栓形成方面有效。该十年期间的手术死亡率为1.2%。随访时间从1个月到104个月不等,86%的患者存活,87%的患者无症状。