Penn R G, Giger D K, Knoop F C, Preheim L C
J Clin Microbiol. 1982 May;15(5):869-72. doi: 10.1128/jcm.15.5.869-872.1982.
An 83-year-old male presented with chronic diarrhea and protein malnutrition associated with Plesiomonas shigelloides overgrowth in the small intestine. This overgrowth was related to achlorhydria and small-bowel diverticula. Tests for heat-labile and heat-stable enterotoxin were negative on the P. shigelloides isolated from both the small bowel aspirate (3 x 10(8) bacteria per ml) and the patient's stool. The patient responded satisfactorily to tetracycline, to which this unusual isolate was susceptible in vitro. The ability to correctly identify and determine the antimicrobial susceptibility of P. shigelloides in the setting of small-bowel overgrowth will help determine appropriate therapy.
一名83岁男性因慢性腹泻和蛋白质营养不良就诊,其小肠内存在弗氏志贺邻单胞菌过度生长。这种过度生长与胃酸缺乏和小肠憩室有关。从小肠吸出物(每毫升含3×10⁸个细菌)和患者粪便中分离出的弗氏志贺邻单胞菌,其耐热和不耐热肠毒素检测均为阴性。该患者对四环素反应良好,此不常见的分离株在体外对四环素敏感。在小肠过度生长的情况下正确鉴定弗氏志贺邻单胞菌并确定其抗菌药敏性,将有助于确定合适的治疗方法。