Center for Sustainable Futures, Istituto Italiano di Tecnologia, 10129, Turin, Italy.
Department of Applied Science and Technology, Politecnico di Torino, 10129, Turin, Italy.
J Biomed Mater Res B Appl Biomater. 2017 Nov;105(8):2244-2253. doi: 10.1002/jbm.b.33756. Epub 2016 Jul 26.
Three different single-lumen double-J ureteral stents of different materials were studied and compared after the insertion into a dynamic in vitro model with sterile artificial urine up to 6 months. The aim was to evaluate, at selected time steps of 1, 3, and 6 months, the material performances of the stents in preventing the formation of inorganic encrustations. Morphological, compositional, and qualitative analyses were carried out both before stent insertion and after stent permanence for the different time steps, showing an increasing level of encrustation which remains particularly low in the case of two polyurethane stents. Mechanical tests show that both the polyurethane stents and the chitosan one do not decrease the tensile strength after 6 months of indwelling. Evaluation of the wetting behavior of the stent outer surfaces indicates a hydrophilic behavior in most of the cases, which is generally preserved after immersion in artificial urine for the different time steps. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 2244-2253, 2017.
研究并比较了三种不同材料的单腔双 J 输尿管支架，将其插入无菌人工尿液的动态体外模型中，最长可达 6 个月。目的是评估支架在防止无机沉淀物形成方面的材料性能，在支架插入前和不同时间点（1、3 和 6 个月）后进行形态学、组成和定性分析，结果显示，随着时间的推移，沉淀物的含量逐渐增加，但在两种聚氨酯支架的情况下，沉淀物含量仍然特别低。机械测试表明，两种聚氨酯支架和壳聚糖支架在留置 6 个月后，拉伸强度均未下降。对支架外表面润湿行为的评估表明，大多数情况下支架具有亲水性，在不同时间点浸入人工尿液后，这种亲水性通常得以保持。2016 年 Wiley 期刊公司。生物医学材料研究杂志 B 辑：应用生物材料，105B:2244-2253，2017 年。
