• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

基于金纳米海绵的多刺激响应型药物载体用于靶向化学生物治疗。

Gold-Nanosponge-Based Multistimuli-Responsive Drug Vehicles for Targeted Chemo-Photothermal Therapy.

机构信息

State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jiangsu, 210093, China.

Department of Chemistry and Biochemistry, University of South Carolina, Columbia, SC, 29208, USA.

出版信息

Adv Mater. 2016 Oct;28(37):8218-8226. doi: 10.1002/adma.201602486. Epub 2016 Jul 27.

DOI:10.1002/adma.201602486
PMID:27459898
Abstract

Gold-nanosponge-based multistimuli-responsive drug vehicles are constructed for combined chemo-photothermal therapy with pinpointed drug delivery and release capabilities and minimized nonspecific systemic spread of drugs, remarkably enhancing the therapeutic efficiency while minimizing acute side effects.

摘要

基于金纳米海绵的多刺激响应型药物载体具有精确的药物输送和释放能力以及最小化药物的非特异性全身扩散，用于联合化学-光热治疗，显著提高治疗效率，同时最小化急性副作用。

相似文献

1
Gold-Nanosponge-Based Multistimuli-Responsive Drug Vehicles for Targeted Chemo-Photothermal Therapy.基于金纳米海绵的多刺激响应型药物载体用于靶向化学生物治疗。
Adv Mater. 2016 Oct;28(37):8218-8226. doi: 10.1002/adma.201602486. Epub 2016 Jul 27.
2
Multistimuli-responsive drug vehicles based on gold nanoflowers for chemophotothermal synergistic cancer therapy.基于金纳米花的多刺激响应型药物载体用于化学光热协同癌症治疗。
Nanomedicine (Lond). 2018 Aug;13(16):1967-1983. doi: 10.2217/nnm-2018-0067. Epub 2018 Sep 18.
3
BSA-based CuSe nanoparticles with multistimuli-responsive drug vehicles for synergistic chemo-photothermal therapy.基于 BSA 的 CuSe 纳米粒子作为多刺激响应型药物载体用于协同化学-光热治疗。
Colloids Surf B Biointerfaces. 2018 Dec 1;172:298-307. doi: 10.1016/j.colsurfb.2018.07.041. Epub 2018 Jul 19.
4
A multi-stimuli responsive gold nanocage-hyaluronic platform for targeted photothermal and chemotherapy.一种用于靶向光热和化疗的多刺激响应金纳米笼-透明质酸平台。
Biomaterials. 2014 Dec;35(36):9678-88. doi: 10.1016/j.biomaterials.2014.08.013. Epub 2014 Aug 28.
5
Rattle-Type Gold Nanorods/Porous-SiO Nanocomposites as Near-Infrared Light-Activated Drug Delivery Systems for Cancer Combined Chemo-Photothermal Therapy. rattled 型金纳米棒/多孔硅纳米复合材料作为近红外光激活的药物输送系统用于癌症联合化疗-光热治疗。
Mol Pharm. 2019 May 6;16(5):1929-1938. doi: 10.1021/acs.molpharmaceut.8b01298. Epub 2019 Apr 4.
6
Porous Au@Pt Nanoparticles: Therapeutic Platform for Tumor Chemo-Photothermal Co-Therapy and Alleviating Doxorubicin-Induced Oxidative Damage.多孔 Au@Pt 纳米粒子：用于肿瘤化学-光热协同治疗和缓解阿霉素诱导的氧化损伤的治疗平台。
ACS Appl Mater Interfaces. 2018 Jan 10;10(1):150-164. doi: 10.1021/acsami.7b14705. Epub 2017 Dec 29.
7
Gold nanoparticle-gated mesoporous silica as redox-triggered drug delivery for chemo-photothermal synergistic therapy.载金纳米粒子介孔硅作为氧化还原触发的药物递送用于化学-光热协同治疗。
J Colloid Interface Sci. 2017 Dec 15;508:323-331. doi: 10.1016/j.jcis.2017.08.050. Epub 2017 Aug 16.
8
Gold modified polydopamine coated mesoporous silica nano-structures for synergetic chemo-photothermal effect.金修饰的聚多巴胺包覆的介孔硅纳米结构用于协同化学-光热效应。
Colloids Surf B Biointerfaces. 2018 Nov 1;171:176-185. doi: 10.1016/j.colsurfb.2018.07.015. Epub 2018 Jul 10.
9
A light-controllable specific drug delivery nanoplatform for targeted bimodal imaging-guided photothermal/chemo synergistic cancer therapy.一种光控的靶向双模态成像引导光热/化疗协同治疗的特异药物递送纳米平台。
Acta Biomater. 2018 Oct 15;80:308-326. doi: 10.1016/j.actbio.2018.09.024. Epub 2018 Sep 19.
10
Mesoporous silica-coated gold nanostars with drug payload for combined chemo-photothermal cancer therapy.载药介孔硅壳金纳米星用于联合化疗-光热癌症治疗
J Drug Target. 2019 Feb;27(2):201-210. doi: 10.1080/1061186X.2018.1499746. Epub 2018 Aug 20.

引用本文的文献

1
Advances in targeted therapy for tumor with nanocarriers: A review.纳米载体用于肿瘤靶向治疗的研究进展：综述
Mater Today Bio. 2025 Feb 15;31:101583. doi: 10.1016/j.mtbio.2025.101583. eCollection 2025 Apr.
2
Neoadjuvant Gold Nanoshell-Based Photothermal Therapy Combined with Liposomal Doxorubicin in a Mouse Model of Colorectal Cancer.基于金纳米壳的新辅助光热治疗联合脂质体多柔比星在结直肠癌小鼠模型中的应用。
Int J Nanomedicine. 2023 Feb 17;18:829-841. doi: 10.2147/IJN.S389260. eCollection 2023.
3
Shape controlled synthesis of concave octahedral Au@AuAg nanoparticles to improve their surface-enhanced Raman scattering performance.
形状可控合成凹面八面体Au@AuAg纳米颗粒以提高其表面增强拉曼散射性能。
RSC Adv. 2022 Jul 6;12(30):19571-19578. doi: 10.1039/d2ra02651a. eCollection 2022 Jun 29.
4
Physical process-aided fabrication of periodic Au-M (M = Ag, Cu, Ag-Cu) alloyed nanoparticle arrays with tunable localized surface plasmon resonance and diffraction peaks.物理过程辅助制备具有可调谐局域表面等离子体共振和衍射峰的周期性金-金属（M = 银、铜、银-铜）合金纳米颗粒阵列
RSC Adv. 2018 Mar 1;8(17):9134-9140. doi: 10.1039/c7ra13567j. eCollection 2018 Feb 28.
5
SERS Tags for Biomedical Detection and Bioimaging.用于生物医学检测和生物成像的 SERS 标签
Theranostics. 2022 Jan 24;12(4):1870-1903. doi: 10.7150/thno.66859. eCollection 2022.
6
Design and Application of Near-Infrared Nanomaterial-Liposome Hybrid Nanocarriers for Cancer Photothermal Therapy.用于癌症光热治疗的近红外纳米材料-脂质体混合纳米载体的设计与应用
Pharmaceutics. 2021 Dec 3;13(12):2070. doi: 10.3390/pharmaceutics13122070.
7
Gold Nanoframeworks with Mesopores for Raman-Photoacoustic Imaging and Photo-Chemo Tumor Therapy in the Second Near-Infrared Biowindow.具有介孔的金纳米框架用于二次近红外生物窗口中的拉曼-光声成像和光化学肿瘤治疗
Adv Funct Mater. 2020 Feb 26;30(9). doi: 10.1002/adfm.201908825. Epub 2020 Jan 8.
8
Sialic acid-engineered mesoporous polydopamine nanoparticles loaded with SPIO and Fe as a novel theranostic agent for T1/T2 dual-mode MRI-guided combined chemo-photothermal treatment of hepatic cancer.负载超顺磁性氧化铁和铁的唾液酸工程化介孔聚多巴胺纳米粒子作为一种新型诊疗剂用于T1/T2双模态磁共振成像引导下的肝癌联合化疗-光热治疗
Bioact Mater. 2020 Nov 10;6(5):1423-1435. doi: 10.1016/j.bioactmat.2020.10.020. eCollection 2021 May.
9
Constructing CuS@SiO/DOX Multifunctional Nanoplatforms for Synergistic Photothermal-Chemotherapy on Melanoma Tumors.构建用于黑色素瘤肿瘤协同光热-化疗的硫化铜@二氧化硅/阿霉素多功能纳米平台。
Front Bioeng Biotechnol. 2020 Sep 15;8:579439. doi: 10.3389/fbioe.2020.579439. eCollection 2020.
10
NIR Stimulus-Responsive PdPt Bimetallic Nanoparticles for Drug Delivery and Chemo-Photothermal Therapy.用于药物递送和化疗-光热疗法的近红外刺激响应性钯铂双金属纳米颗粒
Pharmaceutics. 2020 Jul 17;12(7):675. doi: 10.3390/pharmaceutics12070675.