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基于金纳米海绵的多刺激响应型药物载体用于靶向化学生物治疗。

Gold-Nanosponge-Based Multistimuli-Responsive Drug Vehicles for Targeted Chemo-Photothermal Therapy.

机构信息

State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jiangsu, 210093, China.

Department of Chemistry and Biochemistry, University of South Carolina, Columbia, SC, 29208, USA.

出版信息

Adv Mater. 2016 Oct;28(37):8218-8226. doi: 10.1002/adma.201602486. Epub 2016 Jul 27.

DOI:10.1002/adma.201602486
PMID:27459898
Abstract

Gold-nanosponge-based multistimuli-responsive drug vehicles are constructed for combined chemo-photothermal therapy with pinpointed drug delivery and release capabilities and minimized nonspecific systemic spread of drugs, remarkably enhancing the therapeutic efficiency while minimizing acute side effects.

摘要

基于金纳米海绵的多刺激响应型药物载体具有精确的药物输送和释放能力以及最小化药物的非特异性全身扩散，用于联合化学-光热治疗，显著提高治疗效率，同时最小化急性副作用。

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[3]
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[4]
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[5]
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[6]
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[7]
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[8]
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