达比加群可导致嗜酸性粒细胞性胸腔和心包积液，并伴有血液嗜酸性粒细胞增多。

Dabigatran can cause eosinophilic pleural and pericardial effusion with blood eosinophilia.

作者信息

Voulgaris Thanasis, Anevlavis Stavros, Karpathiou Georgia, Forest Fabien, Koulelidis Andreas, Froudarakis Marios

机构信息

Department of Respiratory Medicine, Medical School, Democritus University of Thrace, Alexandroupolis 68100, Greece.

Department of Pathology, North Hospital, University Hospital of St. Etienne, St-Etienne, France.

出版信息

Clin Respir J. 2018 Feb;12(2):799-801. doi: 10.1111/crj.12537. Epub 2016 Aug 8.

DOI:10.1111/crj.12537

PMID:27460941

Abstract

Eosinophilic pleural effusions (EPE) account for 5%-8% of all exudative pleural effusions. A pleural effusion is defined as eosinophilic if it contains 10% or more eosinophils. We present the case of a 70-year-old man with EPE, blood eosinophilia and pericardial effusion due to dabigatran, a novel anti-thrombin agent.

摘要

嗜酸性胸腔积液（EPE）占所有渗出性胸腔积液的5%-8%。如果胸腔积液中嗜酸性粒细胞含量达到10%或更多，则被定义为嗜酸性胸腔积液。我们报告一例70岁男性患者，因新型抗凝血酶药物达比加群导致嗜酸性胸腔积液、血液嗜酸性粒细胞增多及心包积液。