López-Valverde Gloria, Garcia-Martin Elena, Larrosa-Povés José Manuel, Polo-Llorens Vicente, Pablo-Júlvez Luis E
Hospital Royo Villanova, Zaragoza, Spain; Hospital Universitario Miguel Servet, Zaragoza, Spain.
Hospital Universitario Miguel Servet, Zaragoza, Spain; Instituto de Investigación Sanitaria de Aragón (IIS Aragon), Zaragoza, Spain.
Case Rep Ophthalmol. 2016 May 2;7(1):237-42. doi: 10.1159/000446104. eCollection 2016 Jan-Apr.
The purpose of this study is to describe a case of ocular rosacea with a very complex evolution. Rosacea is a chronic dermatological disease that may affect the ocular structures up to 6-72% of all cases. This form is often misdiagnosed, which may lead to long inflammatory processes with important visual consequences for affected patients. Therefore, an early diagnosis and an adequate treatment are important.
We report the case of a 43-year-old patient who had several relapses of what seemed an episode of acute bacterial conjunctivitis. Two weeks later, he developed a corneal ulcer with a torpid evolution including abundant intrastromal infiltrators and calcium deposits. He was diagnosed with ocular rosacea and treated with systemic doxycycline and topical protopic.
A coating with amniotic membrane was placed in order to heal the ulcer, but a deep anterior lamellar keratoplasty to restore the patient's vision because of the corneal transparency loss was necessary.
Ocular rosacea includes multiple ophthalmic manifestations ranging from inflammation of the eyelid margin and blepharitis to serious corneal affectations. A delayed diagnosis can result in chronic inflammatory conditions including keratinization and loss of corneal transparency, which lead to important visual sequelae for affected patients.
本研究旨在描述一例病情演变极为复杂的眼部酒渣鼻病例。酒渣鼻是一种慢性皮肤病,在所有病例中,眼部结构受影响的比例可达6% - 72%。这种类型常被误诊,这可能导致长期的炎症过程,给受影响患者带来严重的视觉后果。因此,早期诊断和适当治疗至关重要。
我们报告了一例43岁患者的病例,该患者经历了几次看似急性细菌性结膜炎发作的复发。两周后,他出现了角膜溃疡,病情进展缓慢,伴有大量基质内浸润和钙沉积。他被诊断为眼部酒渣鼻,并接受了全身强力霉素和局部他克莫司治疗。
为了愈合溃疡,放置了羊膜覆盖物,但由于角膜透明度丧失,有必要进行深板层角膜移植术以恢复患者视力。
眼部酒渣鼻包括多种眼科表现,从睑缘炎和睑皮炎到严重的角膜病变。延迟诊断可导致慢性炎症状态,包括角膜角化和透明度丧失,这会给受影响患者带来严重的视觉后遗症。