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用于外科激光软组织消融应用的脉冲和连续波可调谐1942纳米单模全光纤掺铥光纤激光系统。

Pulsed and CW adjustable 1942 nm single-mode all-fiber Tm-doped fiber laser system for surgical laser soft tissue ablation applications.

作者信息

Huang Yize, Jivraj Jamil, Zhou Jiaqi, Ramjist Joel, Wong Ronnie, Gu Xijia, Yang Victor X D

出版信息

Opt Express. 2016 Jul 25;24(15):16674-86. doi: 10.1364/OE.24.016674.

Abstract

A surgical laser soft tissue ablation system based on an adjustable 1942 nm single-mode all-fiber Tm-doped fiber laser operating in pulsed or CW mode with nitrogen assistance is demonstrated. Ex vivo ablation on soft tissue targets such as muscle (chicken breast) and spinal cord (porcine) with intact dura are performed at different ablation conditions to examine the relationship between the system parameters and ablation outcomes. The maximum laser average power is 14.4 W, and its maximum peak power is 133.1 W with 21.3 μJ pulse energy. The maximum CW power density is 2.33 × 10 W/cm and the maximum pulsed peak power density is 2.16 × 10 W/cm. The system parameters examined include the average laser power in CW or pulsed operation mode, gain-switching frequency, total ablation exposure time, and the input gas flow rate. The ablation effects were measured by microscopy and optical coherence tomography (OCT) to evaluate the ablation depth, superficial heat-affected zone diameter (HAZD) and charring diameter (CD). Our results conclude that the system parameters can be tailored to meet different clinical requirements such as ablation for soft tissue cutting or thermal coagulation for future applications of hemostasis.

摘要

展示了一种基于可调谐1942纳米单模全光纤掺铥光纤激光器的外科激光软组织消融系统,该激光器在氮气辅助下以脉冲或连续波模式运行。在不同消融条件下,对诸如肌肉(鸡胸肉)和硬脑膜完整的脊髓(猪)等软组织目标进行离体消融,以研究系统参数与消融结果之间的关系。激光的最大平均功率为14.4瓦,其最大峰值功率为133.1瓦,脉冲能量为21.3微焦。连续波模式下的最大功率密度为2.33×10瓦/平方厘米,脉冲峰值功率密度为2.16×10瓦/平方厘米。所研究的系统参数包括连续波或脉冲运行模式下的激光平均功率、增益开关频率、总消融暴露时间以及输入气体流速。通过显微镜和光学相干断层扫描(OCT)测量消融效果,以评估消融深度、表面热影响区直径(HAZD)和炭化直径(CD)。我们的结果表明,系统参数可以进行调整,以满足不同的临床需求,例如用于软组织切割的消融或用于未来止血应用的热凝固。

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