Tokuda M, Kurata N, Daikuhara H, Akisawa M, Onishi I, Asano T, Kobayashi S, Ohmori M, Irino S
First Department of Internal Medicine, Kagawa Medical School, Japan.
J Rheumatol. 1989 Apr;16(4):547-9.
Wegener's granulomatosis is a disease characterized by necrotizing vasculitis and granulomatous inflammation. Gastrointestinal (GI) involvement is uncommon in this disorder. Only a few cases of perforation of GI tract have been reported, but vasculitis has not been demonstrated to be a cause of perforation in these cases. We report a case of Wegener's granulomatosis in which a single perforation in the terminal ileum was disclosed on laparotomy and active necrotizing vasculitis was found in the submucosal layer of the resected specimen.
韦格纳肉芽肿病是一种以坏死性血管炎和肉芽肿性炎症为特征的疾病。胃肠道受累在这种疾病中并不常见。仅有少数胃肠道穿孔的病例被报道，但在这些病例中血管炎尚未被证实是穿孔的原因。我们报告一例韦格纳肉芽肿病患者，该患者在剖腹手术中发现回肠末端有一处穿孔，并且在切除标本的黏膜下层发现了活动性坏死性血管炎。
