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Overexpression of a non-native deoxyxylulose-dependent vitamin B6 pathway in Bacillus subtilis for the production of pyridoxine.在枯草芽孢杆菌中过表达非天然的依赖脱氧木酮糖的维生素B6途径以生产吡哆醇。
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Bacillus subtilis: from soil bacterium to super-secreting cell factory.枯草芽孢杆菌：从土壤细菌到超级分泌细胞工厂。
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From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later.从群体序列到统一序列：十年后的枯草芽孢杆菌168参考基因组
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Regulation of a Bacillus subtilis mobile genetic element by intercellular signaling and the global DNA damage response.通过细胞间信号传导和全局DNA损伤反应对枯草芽孢杆菌移动遗传元件的调控。
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枯草芽孢杆菌枯草亚种菌株∆6的全基因组序列

Complete Genome Sequence of Bacillus subtilis subsp. subtilis Strain ∆6.

作者信息

Reuß Daniel R, Thürmer Andrea, Daniel Rolf, Quax Wim J, Stülke Jörg

机构信息

Department of General Microbiology, Georg-August-University Göttingen, Göttingen, Germany.

Department of Genomics and Applied Microbiology and Göttingen Genomics Laboratory, Georg-August-University Göttingen, Göttingen, Germany.

出版信息

Genome Announc. 2016 Jul 28;4(4):e00759-16. doi: 10.1128/genomeA.00759-16.

DOI:10.1128/genomeA.00759-16
PMID:27469946
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4966479/
Abstract

Bacillus subtilis ∆6 is a genome-reduced strain that was cured from six prophages and AT-rich islands. This strain is of great interest for biotechnological applications. Here, we announce the full-genome sequence of this strain. Interestingly, the conjugative element ICEBs1 has most likely undergone self-excision in B. subtilis ∆6.

摘要

枯草芽孢杆菌∆6是一种经过六个原噬菌体和富含AT的区域消除处理后的基因组精简菌株。该菌株在生物技术应用方面具有重大意义。在此，我们公布该菌株的全基因组序列。有趣的是，接合元件ICEBs1很可能在枯草芽孢杆菌∆6中经历了自我切除。