Baniak Nick, Kanthan Rani
From the Department of Pathology and Laboratory Medicine, College of Medicine, University of Saskatchewan, Saskatoon, Canada.
Arch Pathol Lab Med. 2016 Aug;140(8):854-8. doi: 10.5858/arpa.2015-0176-RS.
Cytomegalovirus latency, though ubiquitous in the human population, is known to cause colitis in both immunocompromised and immunocompetent hosts. Furthermore, the clinical, endoscopic, and histologic appearance of cytomegalovirus colitis can mimic that of inflammatory bowel disease, an extremely well-documented disease. In this context, though many reports have looked at inflammatory bowel disease with superimposed cytomegalovirus infection, less attention has been paid to cytomegalovirus as a primary cause of isolated colitis. Owing to the rarity of this phenomenon, it is important to consider this diagnosis and implement proper testing to avoid misdiagnosis and mismanagement.
巨细胞病毒潜伏感染在人群中普遍存在，已知其在免疫功能低下和免疫功能正常的宿主中均可引起结肠炎。此外，巨细胞病毒结肠炎的临床、内镜及组织学表现可类似于炎症性肠病，后者是一种有大量文献记载的疾病。在此背景下，尽管许多报告关注的是合并巨细胞病毒感染的炎症性肠病，但对于巨细胞病毒作为孤立性结肠炎的主要病因关注较少。由于这种现象罕见，考虑这一诊断并进行适当检测以避免误诊和管理不当很重要。
