Bedolla-Barajas M, Valdez-López F, Alcalá-Padilla G, Bedolla-Pulido T I, Rivera-Mejia V, Morales-Romero J
Servicio de Alergia e Inmunología Clínica, Nuevo Hospital Civil de Guadalajara "Dr. Juan I. Menchaca", Salvador de Quevedo y Zubieta No. 750, Colonia La Perla, Guadalajara, Jalisco, C.P. 44340, Mexico.
Servicio de Alergología e Inmunología Clínica, Hospital Civil de Guadalajara "Fray Antonio Alcalde", Coronel Calderón No. 777, Colonia El Retiro, Guadalajara, Jalisco, C.P. 44280, Mexico.
Allergol Immunopathol (Madr). 2017 Jan-Feb;45(1):69-76. doi: 10.1016/j.aller.2016.04.013. Epub 2016 Jul 28.
In our country, the prevalence and the factors associated to peanut allergy are unknown, a health problem that has been emerging worldwide.
To establish the prevalence and the factors that are associated to peanut allergy amongst school children.
This is a population-based cross-sectional study. We included 756 children aged 6-7 years. The children's parents were questioned about their peanut intake habits. A structured questionnaire was applied, it included questions regarding peanut intake; family and personal history of asthma; rhinitis; and atopic dermatitis. Allergic reactions to peanuts were registered as: probable, convincing and systematic. The statistical analyses included logistical regression models to look for associated factors.
Males were 356/756 (47.1%). Peanut allergy prevalence: probable reaction: 14/756 (1.8%), convincing reaction: 8/756 (1.1%) and systemic reaction: 3/756 (0.4%). Through multivariate analysis, the presence of symptoms of allergic rhinitis (OR=4.2 95% CI 1.3-13.2) and atopic dermatitis (OR=5.2; 95% CI 1.4-19.5) during the previous year, showed significant association to probable peanut reaction. The former year, the presence of atopic dermatitis was the only variable that was substantially associated to a convincing reaction (OR=7.5; 95% CI 1.4-38.4) and to a systematic reaction (OR=45.1; 95% CI 4.0-510.0), respectively.
The reported prevalence of peanut allergy was consistent with that found in previous studies; symptoms of allergic rhinitis and atopic dermatitis were identified as associated factors to peanut allergy.
在我国，花生过敏的患病率及其相关因素尚不清楚，这是一个在全球范围内日益凸显的健康问题。
确定学龄儿童中花生过敏的患病率及其相关因素。
这是一项基于人群的横断面研究。我们纳入了756名6至7岁的儿童。询问了儿童家长他们的花生摄入习惯。应用了一份结构化问卷，其中包括关于花生摄入的问题；哮喘、鼻炎和特应性皮炎的家族史和个人史。对花生的过敏反应被记录为：可能、确定和全身性。统计分析包括使用逻辑回归模型寻找相关因素。
男性有356/756（47.1%）。花生过敏患病率：可能反应为14/756（1.8%），确定反应为8/756（1.1%），全身性反应为3/756（0.4%）。通过多变量分析，前一年出现过敏性鼻炎症状（比值比=4.2；95%置信区间1.3 - 13.2）和特应性皮炎症状（比值比=5.2；95%置信区间1.4 - 19.5）与可能花生反应显著相关。前一年，特应性皮炎的存在是分别与确定反应（比值比=7.5；95%置信区间1.4 - 38.4）和全身性反应（比值比=45.1；95%置信区间4.0 - 510.0）显著相关的唯一变量。
报告的花生过敏患病率与先前研究结果一致；过敏性鼻炎和特应性皮炎症状被确定为花生过敏的相关因素。
