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高强度聚焦超声治疗对良性子宫肿瘤的影响

Effects of High-Intensity-Focused Ultrasound Treatment on Benign Uterine Tumor.

作者信息

Park Jaeyoon, Lee Jae Seong, Cho Jae-Hwan, Kim Sungchul

机构信息

Department of Radiology, Incheon Christian Hospital, Incheon, Korea.; Department of Radiological Science, Gachon University Medical Campus, Incheon, Korea.

Department of Obstetrics and Gynaecology, Aegis Womanmed Clinic, Seoul, Korea .

出版信息

J Korean Med Sci. 2016 Aug;31(8):1279-83. doi: 10.3346/jkms.2016.31.8.1279. Epub 2016 Jun 7.

Abstract

In this study, the effects of high-intensity-focused ultrasound (HIFU) treatment on benign uterine tumor patients were examined. A total of 333 patients diagnosed with fibroids or adenomyosis using diagnostic sonography, treated with HIFU between February 4, 2010 and December 29, 2014 at a hospital in Korea, and followed up for three or six months were selected for this study. Their benign uterine tumor volume was measured, and the effects of HIFU treatment on the volume were analyzed according to age, disease, fertility, and treatment duration. The volume of benign tumors of the uterus changed by age in all age groups after conducting HIFU treatment for 3 and 6 months, respectively. The rate of decrease in individuals' in their twenties was the largest, at 64.9%. When the decreasing volume of benign tumors of the uterus was analyzed by type of disease, the treatment efficacy for adenomyosis was the best, with a decrease of 164.83 cm(3) after 6 months. Myoma had the fastest decreasing rate, at 68.5%. When evaluated on the basis of fertility, the volume of benign tumors of the uterus continued to decrease until 6 months after completing all procedures. The volume has continued to decrease for 6 months after all procedures. This study showed that HIFU treatments for uterine fibroid and adenomyosis is an effective non-invasive therapy via reducing the benign uterine tumor volume. Therefore, the HIFU method might replace other conventional treatment methods.

摘要

在本研究中,检测了高强度聚焦超声(HIFU)治疗对子宫良性肿瘤患者的影响。选取了2010年2月4日至2014年12月29日期间在韩国一家医院接受HIFU治疗并随访3个月或6个月的333例经诊断性超声检查确诊为子宫肌瘤或子宫腺肌病的患者。测量了他们子宫良性肿瘤的体积,并根据年龄、疾病、生育情况和治疗持续时间分析了HIFU治疗对体积的影响。分别在进行HIFU治疗3个月和6个月后,所有年龄组子宫良性肿瘤的体积均随年龄发生了变化。二十多岁患者的肿瘤体积缩小率最大,为64.9%。按疾病类型分析子宫良性肿瘤体积的减小情况时,子宫腺肌病的治疗效果最佳,6个月后体积减小164.83 cm³。子宫肌瘤的体积减小速度最快,为68.5%。以生育情况为基础进行评估时,子宫良性肿瘤的体积在完成所有治疗后的6个月内持续减小。所有治疗完成后,体积持续减小6个月。本研究表明,HIFU治疗子宫肌瘤和子宫腺肌病是一种通过减小子宫良性肿瘤体积的有效非侵入性疗法。因此,HIFU方法可能会取代其他传统治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f267/4951559/c2fa6da1a109/jkms-31-1279-g001.jpg

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