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基于延迟发光的中草药光谱分析

Spectral Analysis of Chinese Medicinal Herbs Based on Delayed Luminescence.

作者信息

Pang Jingxiang, Zhu Xiaoyan, Liu Yanli, Fu Jialei, Zhao Xiaolei, Yang Meina, van Wijk Eduard, Wang Mei, Nie Xiaoyan, Han Jinxiang

机构信息

Shandong Medicinal Biotechnology Center, Key Laboratory for Biotech-Drugs, Ministry of Health, Shandong Academy of Medical Sciences, Jinan, Shandong 250062, China.

Shandong Center for Disease Control and Prevention, Jinan, Shandong 250014, China.

出版信息

Evid Based Complement Alternat Med. 2016;2016:8469024. doi: 10.1155/2016/8469024. Epub 2016 Jul 11.

Abstract

Traditional Chinese medicine (TCM) plays a critical role in healthcare; however, it lacks scientific evidence to support the multidimensional therapeutic effects. These effects are based on experience, and, to date, there is no advanced tool to evaluate these experience based effects. In the current study, Chinese herbal materials classified with different cold and heat therapeutic properties, based on Chinese medicine principles, were investigated using spectral distribution, as well as the decay probability distribution based on delayed luminescence (DL). A detection system based on ultraweak biophoton emission was developed to determine the DL decay kinetics of the cold and heat properties of Chinese herbal materials. We constructed a mathematical model to fit the experimental data and characterize the properties of Chinese medicinal herbs with different parameters. The results demonstrated that this method has good reproducibility. Moreover, there is a significant difference (p < 0.05) in the spectral distribution and the decay probability distribution of Chinese herbal materials with cold and heat properties. This approach takes advantage of the comprehensive nature of DL compared with more reductionist approaches and is more consistent with TCM principles, in which the core comprises holistic views.

摘要

传统中医(TCM)在医疗保健中发挥着关键作用;然而,它缺乏科学证据来支持其多维度的治疗效果。这些效果基于经验,并且迄今为止,尚无先进工具来评估这些基于经验的效果。在当前研究中,根据中医理论,对具有不同寒热治疗特性分类的中药材,利用光谱分布以及基于延迟发光(DL)的衰减概率分布进行了研究。开发了一种基于超微弱生物光子发射的检测系统,以确定中药材寒热特性的DL衰减动力学。我们构建了一个数学模型来拟合实验数据,并通过不同参数表征中药材的特性。结果表明该方法具有良好的重现性。此外,具有寒热特性的中药材在光谱分布和衰减概率分布上存在显著差异(p < 0.05)。与更简化的方法相比,这种方法利用了DL的综合性,并且更符合中医理论,中医理论的核心包含整体观。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4cc/4958485/4278240618ed/ECAM2016-8469024.001.jpg

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