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精神病患者功能改善的预测因素:动机缺乏和失败主义表现信念的作用。

Predictors of improved functioning in patients with psychosis: The role of amotivation and defeatist performance beliefs.

机构信息

Clinical Psychology and Psychotherapy, Institute of Psychology, Universität Hamburg, Hamburg, Germany.

Clinical Psychology and Psychotherapy, Institute of Psychology, Universität Hamburg, Hamburg, Germany.

出版信息

Psychiatry Res. 2016 Oct 30;244:117-22. doi: 10.1016/j.psychres.2016.07.018. Epub 2016 Jul 12.

Abstract

Defeatist performance beliefs (DPBs) are associated with the severe impairments in functioning of patients with negative symptoms of schizophrenia. This association has been found to be mediated by amotivation, a core aspect of negative symptoms. Although causality is assumed, longitudinal evidence for this is lacking. The current study aimed to extend previous findings by investigating both cross-sectional and longitudinal associations between DPBs, motivational impairments and functioning in a sample of patients with psychotic disorders (N=58). We hypothesized, that DPBs would be related to functioning in cross-sectional and longitudinal analyses and that this link would be mediated by motivational impairments. Data was assessed at baseline and post-treatment in a trial on the effects of cognitive behavior therapy for psychosis. At baseline, amotivation mediated the association between DPBs and functioning. From baseline to post-treatment, reduction of amotivation was associated with improvement of functioning significantly, whereas reduction of DPBs was unrelated to improvements in functioning or amotivation. The findings suggest that improvement in amotivation accounts for favorable treatment outcomes in regard to functioning but question the causal role of DPBs in negative symptoms and functioning.

摘要

失败主义表现信念(DPBs)与精神分裂症阴性症状患者功能严重受损有关。这种关联被发现是通过动机不足来介导的,动机不足是阴性症状的一个核心方面。尽管假设存在因果关系,但缺乏纵向证据。本研究旨在通过在精神病患者样本中(N=58)调查 DPBs、动机障碍与功能之间的横断面和纵向关联,扩展先前的发现。我们假设 DPBs 在横断面和纵向分析中与功能相关,并且这种关联是由动机障碍介导的。在一项关于认知行为疗法对精神病影响的试验中,数据在基线和治疗后进行评估。在基线时,动机不足介导了 DPBs 与功能之间的关联。从基线到治疗后,动机不足的减少与功能的显著改善显著相关,而 DPBs 的减少与功能或动机不足的改善无关。研究结果表明,动机不足的改善可以解释治疗结果在功能方面的改善,但对 DPBs 在阴性症状和功能中的因果作用提出了质疑。

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