Barnard B J, Bengis R G, Griessel M D, de Vos V
Veterinary Research Institute, Onderstepoort.
Onderstepoort J Vet Res. 1989 Jun;56(2):131-4.
Excretion of alcelaphine herpesvirus-1 (AHV-1) is for all practical purposes limited to wildebeest calves under the age of 4 months. Sixty-one per cent of calves 1-2 months of age excreted virus with a mean titre of 9.8 X 10(4) cytopathic-forming foci/ml in their ocular fluid. The incidence declined sharply to less than 2% in wildebeest older than 6 months. No difference in age-related excretion of virus could be detected between free-living and captive wildebeest and no virus could be isolated from free-living pregnant wildebeest cows or from captive cows and their calves during the first 4 weeks after birth. The occurrence of wildebeest-derived malignant catarrhal fever (WD MCF) during spring, when wildebeest do not excrete virus, is a strong indication of the existence of an alternative host or an intermediate host capable of biological transfer of AHV-1.
实际上，黑尾牛羚疱疹病毒1型（AHV - 1）的排泄仅限于4个月龄以下的小牛羚。1至2月龄的小牛羚中有61%排泄病毒，其眼液中的平均滴度为9.8×10⁴个细胞病变形成灶/毫升。在6个月龄以上的牛羚中，发病率急剧下降至不到2%。在自由放养和圈养的牛羚之间，未检测到与年龄相关的病毒排泄差异，并且在出生后的前4周内，无法从自由放养的怀孕牛羚母牛或圈养母牛及其小牛中分离出病毒。在春季牛羚不排泄病毒时发生源自牛羚的恶性卡他热（WD MCF），这有力地表明存在能够进行AHV - 1生物传播的替代宿主或中间宿主。
