中间体残余物调控上皮细胞中初级纤毛的形成。
Midbody remnant licenses primary cilia formation in epithelial cells.
作者信息
Ott Carolyn M
机构信息
Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147
出版信息
J Cell Biol. 2016 Aug 1;214(3):237-9. doi: 10.1083/jcb.201607046.
Abstract
Tethered midbody remnants dancing across apical microvilli, encountering the centrosome, and beckoning forth a cilium-who would have guessed this is how polarized epithelial cells coordinate the end of mitosis and the beginning of ciliogenesis? New evidence from Bernabé-Rubio et al. (2016. J. Cell Biol http://dx.doi.org/10.1083/jcb.201601020) supports this emerging model.
摘要
被束缚的中体残余物在顶端微绒毛间舞动，与中心体相遇，并促使纤毛伸出——谁能想到极化上皮细胞就是这样协调有丝分裂结束和纤毛发生起始的呢？伯纳贝 - 鲁维奥等人（2016年。《细胞生物学杂志》http://dx.doi.org/10.1083/jcb.201601020）的新证据支持了这一新兴模型。
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