Scott Ryan, Enns Robert
Dr Scott is a therapeutic endoscopy fellow and Dr Enns is a clinical professor of medicine in the Division of Gastroenterology at St Paul's Hospital and the University of British Columbia in Vancouver, Canada.
Gastroenterol Hepatol (N Y). 2015 Sep;11(9):612-7.
Wireless video capsule endoscopy (VCE) is a minimally invasive technology that has revolutionized the approach to small intestinal disease investigation and management. Designed primarily to provide diagnostic imaging of the small intestine, VCE is used predominantly for obscure gastrointestinal bleeding and suspected Crohn's disease; however, numerous other indications have been established, including the assessment of celiac disease, investigation of small bowel tumors, and surveillance of hereditary polyposis syndromes. Since the introduction of small bowel VCE in 2000, more than 1600 articles have been published describing the evolution of this technology. The main adverse outcome is capsule retention, which can potentially be avoided by careful patient selection or by using a patency capsule. Despite the numerous advances in the past 15 years, limitations such as incomplete VCE studies, missed lesions, and time-consuming reporting remain. The inability to control capsule movement for the application of targeted therapy or the acquisition of tissue for histologic analysis remains among the greatest challenges in the further development of capsule technology. This article outlines the recent technological and clinical advances in VCE and the future directions of research in this field.
无线视频胶囊内镜检查（VCE）是一项微创技术，它彻底改变了小肠疾病的检查和治疗方法。VCE主要用于提供小肠的诊断成像，主要用于不明原因的胃肠道出血和疑似克罗恩病；然而，已经确定了许多其他适应症，包括乳糜泻的评估、小肠肿瘤的检查以及遗传性息肉病综合征的监测。自2000年小肠VCE问世以来，已经发表了1600多篇描述该技术发展的文章。主要不良后果是胶囊滞留，通过仔细选择患者或使用通畅胶囊有可能避免这种情况。尽管在过去15年中有众多进展，但仍存在一些局限性，如VCE研究不完整、病变漏诊和报告耗时等。无法控制胶囊移动以应用靶向治疗或获取组织进行组织学分析仍然是胶囊技术进一步发展面临的最大挑战之一。本文概述了VCE最近的技术和临床进展以及该领域的未来研究方向。
