Collins Paul D
Paul D Collins, Department of Gastroenterology and Hepatology, Royal Liverpool University Hospital, Liverpool L8 7NP, United Kingdom.
World J Gastrointest Endosc. 2016 Jul 25;8(14):477-88. doi: 10.4253/wjge.v8.i14.477.
Video capsule endoscopy (VCE) has evolved to become an important tool for the non-invasive examination of the small bowel, which hitherto had been relatively inaccessible to direct visualisation. VCE has been shown to play a role in monitoring the activity of small bowel Crohn's disease and can be used to assess the response to anti-inflammatory treatment in Crohn's disease. For those patients with Crohn's disease who have undergone an intestinal resection, VCE has been assessed as a tool to detect post-operative recurrence. VCE may also aid in the reclassification of patients with a diagnosis of Inflammatory Bowel Disease Unclassified to Crohn's disease. The evolution of colon capsule endoscopy (CCE) has expanded the application of this technology further. The use of CCE to assess the activity of ulcerative colitis has been described. This advance in capsule technology has also fuelled interest in its potential role as a minimally invasive tool to assess the whole of GI tract opening the possibility of its use for the panenteric assessment of Crohn's disease. VCE is a safe procedure. However, the risk of a retained capsule is higher in patients with suspected or confirmed Crohn's disease compared with patients having VCE examination for other indications. A retained video capsule is rare after successful passage of a patency capsule which may be utilised to pre-screen patients undergoing VCE. This paper describes the use of VCE in the assessment of inflammatory bowel disease.
视频胶囊内镜检查(VCE)已发展成为小肠无创检查的重要工具,此前小肠一直相对难以直接可视化。VCE已被证明在监测小肠克罗恩病的活动中发挥作用,可用于评估克罗恩病抗炎治疗的反应。对于那些接受过肠道切除术的克罗恩病患者,VCE已被评估为检测术后复发的工具。VCE也可能有助于将未分类的炎症性肠病患者重新分类为克罗恩病。结肠胶囊内镜检查(CCE)的发展进一步扩大了这项技术的应用。已描述了使用CCE评估溃疡性结肠炎的活动。胶囊技术的这一进展也激发了人们对其作为评估整个胃肠道的微创工具的潜在作用的兴趣,为其用于克罗恩病的全肠道评估开辟了可能性。VCE是一种安全的检查方法。然而,与因其他适应症进行VCE检查的患者相比,疑似或确诊克罗恩病的患者出现胶囊滞留的风险更高。在通过通畅胶囊成功通过后,滞留视频胶囊很少见,通畅胶囊可用于对接受VCE检查的患者进行预筛查。本文描述了VCE在炎症性肠病评估中的应用。