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近视性脉络膜新生血管:诊断与治疗

MYOPIC CHOROIDAL NEOVASCULARIZATION: Diagnosis and Treatment.

作者信息

Lai Timothy Y Y, Cheung Chui Ming Gemmy

机构信息

*Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Kowloon, Hong Kong; †2010 Retina & Macula Centre, Tsim Sha Tsui, Kowloon, Hong Kong; ‡Singapore National Eye Centre, Singapore; §Eye Academic Clinical Program, Duke-NUS Graduate Medical School, Singapore; ¶Singapore Eye Research Institute, Singapore; and ‖Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

出版信息

Retina. 2016 Sep;36(9):1614-21. doi: 10.1097/IAE.0000000000001227.

Abstract

PURPOSE

To review and summarize the latest developments in the diagnosis and management of myopic choroidal neovascularization (mCNV).

METHODS

A review of the literature was performed, focusing on tests and investigations for diagnosing mCNV, as well as the key treatment options available for mCNV.

RESULTS

Standard essential tests and investigations for diagnosing mCNV include spectral-domain optical coherence tomography for screening, fluorescein angiography for confirmation, and indocyanine green angiography and fundus autofluorescence for providing supplementary information. The current first line treatment of mCNV is the use of anti-vascular endothelial growth factor therapy.

CONCLUSION

Various investigations can assist the differentiation of mCNV from other coexisting retinal pathologies associated with myopia or choroidal neovascularization resulting from other causes. Prompt use of anti-vascular endothelial growth factor therapy has good efficacy and safety in the treatment of mCNV.

摘要

目的

回顾并总结近视性脉络膜新生血管(mCNV)诊断与治疗的最新进展。

方法

进行文献综述,重点关注mCNV的诊断测试与检查,以及mCNV可用的关键治疗选择。

结果

诊断mCNV的标准基本测试与检查包括用于筛查的光谱域光学相干断层扫描、用于确诊的荧光素血管造影,以及用于提供补充信息的吲哚菁绿血管造影和眼底自发荧光。mCNV目前的一线治疗是使用抗血管内皮生长因子疗法。

结论

各种检查有助于鉴别mCNV与其他与近视相关的并存视网膜病变或其他原因导致的脉络膜新生血管。及时使用抗血管内皮生长因子疗法治疗mCNV具有良好的疗效和安全性。

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