Lexa A, Fleurentin J, Lehr P R, Mortier F, Pruvost M, Pelt J M
Planta Med. 1989 Apr;55(2):127-32. doi: 10.1055/s-2006-961904.
According to our results, the traditional therapeutic indications of Eupatorium cannabinum L., choleretic and hepatoprotective effects, have been widely demonstrated. An aqueous extract induces hypercholeresis in the rat, the site of bile formation is canalicular in origin and both bile acid-dependent and bile acid-independent flows could be stimulated; the extract possesses anti-necrotic properties against carbon tetrachloride-induced hepatotoxicity, reducing widely the plasma GPT level in pretreated rats.
根据我们的研究结果，土木香（Eupatorium cannabinum L.）的传统治疗适应症，即利胆和保肝作用，已得到广泛证实。水提取物可诱导大鼠胆汁分泌过多，胆汁形成部位起源于胆小管，胆汁酸依赖性和胆汁酸非依赖性胆汁流动均可受到刺激；该提取物对四氯化碳诱导的肝毒性具有抗坏死特性，可大幅降低预处理大鼠的血浆谷丙转氨酶水平。
