Kocourkova Aneta, Honegr Jan, Kuca Kamil, Danova Jana
Biomedical Research Center, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
Mini Rev Med Chem. 2017;17(5):451-466. doi: 10.2174/1389557516666160801103303.
Vaccination is defined as the administration of an antigenic material in order to stimulate the immune system, leading to the development of adaptive immunity to a pathogen. Vaccines can prevent or reduce morbidity from a vast number of infections. This manuscript presents an analysis of vaccine types and vaccine substances, concentrating on individual components including the active ingredient, adjuvants, preservatives, stabilizers, inactivators, antibiotics, diluents and other substances. While many papers have been published on individual vaccine components, this review provides detail on a wide range of the most commonly-used vaccine ingredients and components that have been tested in clinical trials.
疫苗接种被定义为接种抗原物质以刺激免疫系统，从而产生针对病原体的适应性免疫。疫苗可以预防或降低大量感染导致的发病率。本手稿对疫苗类型和疫苗物质进行了分析，重点关注各个成分，包括活性成分、佐剂、防腐剂、稳定剂、灭活剂、抗生素、稀释剂和其他物质。虽然已经发表了许多关于单个疫苗成分的论文，但本综述详细介绍了在临床试验中测试过的各种最常用的疫苗成分。
