Department of Pharmacy, Noakhali Science and Technology University, Noakhali, Bangladesh.
School of Pharmacy, Monash University Malaysia, Selangor, Malaysia.
BMJ Open. 2016 Aug 3;6(8):e010912. doi: 10.1136/bmjopen-2015-010912.
To assess community pharmacists'/pharmacy technicians' knowledge and perceptions about adverse drug reactions (ADRs) and barriers towards the reporting of such reactions in Dhaka, Bangladesh.
A cross-sectional study was planned to approach potential respondents for the study. A self-administered questionnaire was delivered to community pharmacists/pharmacy technicians (N=292) practising in Dhaka, Bangladesh.
The overall response to the survey was 69.5% (n=203). The majority of the sample was comprised of pharmacy technicians (152, 74.9%) who possessed a diploma in pharmacy, followed by pharmacists (37, 18.2%) and others (12, 5.9%). Overall, 72 (35.5%) of the respondents disclosed that they had experienced an ADR at their pharmacy, yet more than half (105, 51.7%) were not familiar with the existence of an ADR reporting body in Bangladesh. Exploring the barriers to the reporting of ADRs, it was revealed that the top four barriers to ADR reporting were 'I do not know how to report (Relative Importance Index (RII)=0.998)', 'reporting forms are not available (0.996)', 'I am not motivated to report (0.997)' and 'Unavailability of professional environment to discuss about ADR (RII=0.939)'. In addition to these, a majority (141, 69.46%) were not confident about the classification of ADRs (RII=0.889) and were afraid of legal liabilities associated with reporting ADRs (RII=0.806). Moreover, a lack of knowledge about pharmacotherapy and the detection of ADRs was another major factor hindering their reporting (RII=0.731).
The Directorate of Drug Administration in Bangladesh needs to consider the results of this study to help it improve and simplify ADR reporting in Bangladeshi community pharmacy settings.
评估孟加拉国达卡市的社区药剂师/药剂技术员对药物不良反应（ADR）的认识和看法，以及他们报告此类不良反应的障碍。
计划进行一项横断面研究，以接触到研究的潜在受访者。向在孟加拉国达卡执业的社区药剂师/药剂技术员（N=292）发放了一份自我管理式问卷。
对调查的总体回应率为 69.5%（n=203）。大多数样本由药剂技术员（152 名，74.9%）组成，他们拥有药剂学文凭，其次是药剂师（37 名，18.2%）和其他人员（12 名，5.9%）。总体而言，72 名（35.5%）受访者表示他们在自己的药房经历过 ADR，但超过一半（105 名，51.7%）不知道孟加拉国有 ADR 报告机构的存在。在探讨报告 ADR 的障碍时，发现报告 ADR 的前四大障碍是“我不知道如何报告（相对重要性指数（RII）=0.998）”、“报告表不可用（0.996）”、“我没有动力报告（0.997）”和“缺乏讨论 ADR 的专业环境（RII=0.939）”。除此之外，大多数（141 名，69.46%）对 ADR 分类没有信心（RII=0.889），并且担心与报告 ADR 相关的法律责任（RII=0.806）。此外，缺乏药物治疗知识和对 ADR 的检测也是阻碍他们报告的另一个主要因素（RII=0.731）。
孟加拉国药品管理局需要考虑这项研究的结果，以帮助其改善和简化孟加拉国社区药房环境中的 ADR 报告。
