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巴基斯坦药剂师对抗菌药物管理的知识与实践

Knowledge and Practice of Pharmacists toward Antimicrobial Stewardship in Pakistan.

作者信息

Rehman Inayat Ur, Asad Malik Muhammad, Bukhsh Allah, Ali Zahid, Ata Humera, Dujaili Juman Abdulelah, Blebil Ali Qais, Khan Tahir Mehmood

机构信息

School of Pharmacy, Monash University, Jalan Lagoon Selatan, Bandar Sunway, 47500 Selangor, Malaysia.

Department of Pharmacy, Abdul Wali Khan University, Mardan 23200, Pakistan.

出版信息

Pharmacy (Basel). 2018 Oct 23;6(4):116. doi: 10.3390/pharmacy6040116.

Abstract

The irrational use, "over the counter supply", and unregulated supply chains of antimicrobials are contributing toward antimicrobial resistance. Antimicrobial stewardship programs regulate antimicrobials usage to prevent resistance and reduce health care burden. To assess the knowledge and practice of pharmacists' working in various healthcare settings toward antimicrobial stewardship in Pakistan. A cross-sectional study was conducted among pharmacists working in different sectors between March to June 2017. A total of 181 pharmacists participated, of whom ( = 145, 80.1%) were males. The majority of participants were in the 20⁻30 age group ( = 147, 81.2%) and hold Doctor of Pharmacy degrees. More than 80% of pharmacists agreed that "antimicrobial stewardship is essential to improve patient care"; while ( = 159, 87.8%) pharmacists agreed that "pharmacist should be trained on the use of antimicrobial". Close to 90% of pharmacists agreed that "adequate training should be provided to pharmacists on antimicrobial use". Regarding the practice of antimicrobial stewardship, ( = 72, 39.8%) pharmacists often/always "make efforts to prevent or reduce the transmission of infections within the community"; ( = 58, 32%) pharmacists never "dispense antimicrobials without a prescription"; and ( = 60, 32%) pharmacist often/always "communicate with prescribers if unsure about the appropriateness of an antibiotic prescription". : Increased antimicrobial stewardship efforts can both optimize the treatment of infections and reduce adverse events associated with antibiotic use. Pharmacists in Pakistan have good knowledge and adopt positive practices toward antimicrobial stewardship. Pharmacist and other health care professionals should collaborate within multi-disciplinary teams to reduce the problem of antimicrobial resistance and improve the quality of life of patients.

摘要

抗菌药物的不合理使用、“非处方供应”以及不受监管的供应链正在导致抗菌药物耐药性。抗菌药物管理计划对抗菌药物的使用进行规范,以预防耐药性并减轻医疗负担。为评估巴基斯坦不同医疗环境中工作的药剂师对抗菌药物管理的知识和实践情况。2017年3月至6月期间,对不同部门工作的药剂师进行了一项横断面研究。共有181名药剂师参与,其中男性145名(占80.1%)。大多数参与者年龄在20至30岁之间(147名,占81.2%),拥有药学博士学位。超过80%的药剂师同意“抗菌药物管理对于改善患者护理至关重要”;而159名(占87.8%)药剂师同意“药剂师应接受抗菌药物使用方面的培训”。近90%的药剂师同意“应向药剂师提供关于抗菌药物使用的充分培训”。关于抗菌药物管理的实践,72名(占39.8%)药剂师经常/总是“努力预防或减少社区内感染的传播”;58名(占32%)药剂师从不“无处方配药抗菌药物”;60名(占32%)药剂师经常/总是“如果对抗生素处方的适当性不确定,会与开处方者沟通”。结论:加强抗菌药物管理努力既能优化感染治疗,又能减少与抗生素使用相关的不良事件。巴基斯坦的药剂师对抗菌药物管理有良好的知识并采取积极的实践。药剂师和其他医疗保健专业人员应在多学科团队中合作,以减少抗菌药物耐药性问题并改善患者的生活质量。

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