Dorner Franziska, Boschert David, Schneider Alexandra, Hartleb Wibke, Al-Ahmad Ali, Lienkamp Karen
Department of Microsystems Engineering (IMTEK), Albert-Ludwigs-Universität, Georges-Köhler-Allee 103, 79110 Freiburg, Germany and Freiburg Centre for Interactive Materials and Bioinspired Technologies (FIT) Albert-Ludwigs-Universität, Georges-Köhler-Allee 103, 79110 Freiburg, Germany.
Department of Operative Dentistry and Periodontology, Center for Dental Medicine of the Albert-Ludwigs-Universität Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.
ACS Macro Lett. 2015 Dec 15;4(12):1337-1340. doi: 10.1021/acsmacrolett.5b00686. Epub 2015 Nov 17.
Regeneration of functional polymer surfaces after damage or contamination is an unresolved scientific challenge, and also of practical importance. In this proof-of-concept study, we present a method to regenerate a functional surface property using a polymer multi-layer architecture. This is exemplified using antimicrobially active surfaces. The idea is to shed the top layer of the polymer layer stack, like a reptile shedding its skin. The proof-of-concept stack consists of two antimicrobial layers and a degradable interlayer. Shedding of the top layer is enabled by degrading that interlayer. The shedding process was analyzed by quantitative fluorescence microscopy, ellipsometry, and FTIR spectroscopy. Antimicrobial assays revealed that the functionality of the emerging antimicrobial layer was fully retained after shedding.
受损或受污染后功能性聚合物表面的再生是一个尚未解决的科学挑战，同时也具有实际重要性。在这项概念验证研究中，我们展示了一种利用聚合物多层结构再生功能性表面特性的方法。这通过具有抗菌活性的表面进行举例说明。其思路是像爬行动物蜕皮一样去除聚合物层叠结构的顶层。概念验证堆叠结构由两个抗菌层和一个可降解中间层组成。通过降解该中间层来实现顶层的脱落。利用定量荧光显微镜、椭偏仪和傅里叶变换红外光谱对脱落过程进行了分析。抗菌试验表明，脱落后新出现的抗菌层的功能得以完全保留。
