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本文引用的文献

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Emergence of a virulent porcine reproductive and respiratory syndrome virus in vaccinated herds in the United States.美国接种疫苗猪群中出现高致病性猪繁殖与呼吸综合征病毒。
Virus Res. 2015 Dec 2;210:34-41. doi: 10.1016/j.virusres.2015.07.004. Epub 2015 Jul 11.
2
Arterivirus molecular biology and pathogenesis.动脉炎病毒分子生物学与发病机制。
J Gen Virol. 2013 Oct;94(Pt 10):2141-2163. doi: 10.1099/vir.0.056341-0. Epub 2013 Aug 12.
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Geneious Basic: an integrated and extendable desktop software platform for the organization and analysis of sequence data.Geneious Basic：一个集成和可扩展的桌面软件平台，用于组织和分析序列数据。
Bioinformatics. 2012 Jun 15;28(12):1647-9. doi: 10.1093/bioinformatics/bts199. Epub 2012 Apr 27.
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Distribution of genotypes of porcine reproductive and respiratory syndrome virus in Ontario during 2004-2007 and the association between genotype and clinical signs of disease.2004年至2007年期间安大略省猪繁殖与呼吸综合征病毒的基因型分布以及基因型与疾病临床症状之间的关联。
Can J Vet Res. 2010 Apr;74(2):118-23.
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Heterogeneity of porcine reproductive and respiratory syndrome virus: implications for current vaccine efficacy and future vaccine development.猪繁殖与呼吸综合征病毒的异质性：对当前疫苗效力及未来疫苗研发的影响
Vet Microbiol. 2000 Jun 12;74(4):309-29. doi: 10.1016/s0378-1135(00)00196-6.
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Porcine reproductive and respiratory syndrome virus comparison: divergent evolution on two continents.猪繁殖与呼吸综合征病毒比较：两大洲的趋异进化
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7
Differentiation of a porcine reproductive and respiratory syndrome virus vaccine strain from North American field strains by restriction fragment length polymorphism analysis of ORF 5.通过对开放阅读框5进行限制性片段长度多态性分析，区分猪繁殖与呼吸综合征病毒疫苗株与北美田间毒株
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Genetic variation in porcine reproductive and respiratory syndrome virus isolates in the midwestern United States.美国中西部猪繁殖与呼吸综合征病毒分离株的基因变异
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Comparison of the structural protein coding sequences of the VR-2332 and Lelystad virus strains of the PRRS virus.猪繁殖与呼吸综合征病毒VR - 2332株和莱利斯塔德病毒株结构蛋白编码序列的比较
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Mystery swine disease in The Netherlands: the isolation of Lelystad virus.荷兰的神秘猪病：莱利斯塔德病毒的分离
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美国近期出现的高致病性猪繁殖与呼吸综合征病毒变异株的全基因组序列

Complete Genome Sequence of Highly Virulent Porcine Reproductive and Respiratory Syndrome Virus Variants That Recently Emerged in the United States.

作者信息

Workman Aspen M, Smith Timothy P L, Osorio Fernando A, Vu Hiep L X

机构信息

USDA, ARS, U.S. Meat Animal Research Center, Clay Center, Nebraska, USA

USDA, ARS, U.S. Meat Animal Research Center, Clay Center, Nebraska, USA.

出版信息

Genome Announc. 2016 Aug 4;4(4):e00772-16. doi: 10.1128/genomeA.00772-16.

DOI:10.1128/genomeA.00772-16
PMID:27491998
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4974319/
Abstract

A recent outbreak of particularly virulent disease caused by porcine reproductive and respiratory syndrome virus has occurred in swine herds across the United States. We report here the complete genome sequence of eight viral isolates from four Nebraska herds experiencing an outbreak of severe disease in 2016.

摘要

最近，美国各地的猪群中爆发了由猪繁殖与呼吸综合征病毒引起的一种特别致命的疾病。在此，我们报告了2016年来自内布拉斯加州四个猪群中经历严重疾病爆发的八个病毒分离株的完整基因组序列。