Larsen Peter, Goethgen Charlotte B, Rasmussen Sten, Iyer Annika B, Elsoe Rasmus
Department of Occupational Therapy and Physiotherapy, Aalborg University Hospital, Aalborg University, 18-22 Hobrovej., 9000, Aalborg, Denmark.
Clinic for Neuro- and Orthopedic Diseases, Aalborg University Hospital, Aalborg, Denmark.
Arch Orthop Trauma Surg. 2016 Nov;136(11):1539-1546. doi: 10.1007/s00402-016-2550-5. Epub 2016 Aug 8.
Most studies of polytrauma examined highly mixed patient groups. The objective of the present study was to report the development of patient-reported quality of life (QOL), in a patient group with musculoskeletal polytrauma, excluding patients with major thoracic, abdominal, and brain injuries.
The study design was a 1-year cohort follow-up study. Recordings of injury severity were measured with the ISS and NISS. Patient-reported QOL was measured with the questionnaires Eq5d-5L and SF-36 and compared to age-matched reference populations. Moreover, patients return to work status was measured. Data were collected prospectively at discharge, 3, 6, and 12 months.
53 patients were included. The mean age was 42.3 years, ranging from 17 to 78 years. Twelve months after trauma admission, the mean Eq5d-5L index was 0.601 (95 % CI 0.546-0.657). A progressive increasing Eq5d-5L index and SF-36 PCS was observed between the discharge and the 12-month follow-up (p < 0.001). The development in QOL from 6 to 12 months almost shows identically scores. Throughout the study period, patients reported significant worse QOL compared with the established reference population. 32 % of patients have resumed earlier employment status at 1-year follow-up.
Throughout the 12-month observational period, patients reported worse QOL compared to the age-matched reference population. The development of QOL from 6- to 12-month time points almost showed identically scores with only little improvement. At the end of 1-year follow-up, 32 % of patients had resumed prior employment status.
大多数多发伤研究考察的是高度混杂的患者群体。本研究的目的是报告肌肉骨骼多发伤患者群体（不包括有严重胸、腹和脑损伤的患者）中患者报告的生活质量（QOL）的发展情况。
本研究设计为一项为期1年的队列随访研究。使用损伤严重度评分（ISS）和简明损伤定级标准（NISS）来测量损伤严重程度。使用欧洲五维度健康量表（Eq5d-5L）和健康调查简表（SF-36）问卷来测量患者报告的生活质量，并与年龄匹配的参考人群进行比较。此外，还对患者的重返工作状态进行了测量。数据在出院时、3个月、6个月和12个月时前瞻性收集。
纳入了53例患者。平均年龄为42.3岁，范围为17至78岁。创伤入院12个月后，平均Eq5d-5L指数为0.601（95%置信区间0.546 - 0.657）。在出院至12个月随访期间，观察到Eq5d-5L指数和SF-36生理健康综合量表（PCS）呈逐渐上升趋势（p < 0.001）。生活质量从6个月到12个月的发展几乎显示出相同的分数。在整个研究期间，患者报告的生活质量明显低于既定的参考人群。在1年随访时，32%的患者恢复了早期就业状态。
在整个12个月的观察期内，与年龄匹配的参考人群相比，患者报告的生活质量较差。生活质量从6个月到12个月时间点的发展几乎显示出相同的分数，只有微小改善。在1年随访结束时，32%的患者恢复了先前的就业状态。
