Feng Bin, Xie Zhixun, Deng Xianwen, Xie Liji, Xie Zhiqin, Huang Li, Fan Qin, Luo Sisi, Huang Jiaoling, Zhang Yanfang, Zeng Tingting, Wang Sheng, Wang Leyi
Guangxi Key Laboratory of Animal Epidemic Etiology and Diagnostic, Guangxi Veterinary Research Institute, 51 Youai North Rd, Nanning, 530001, Guangxi Zhuang Autonomous Region, China.
Animal Disease Diagnostic Laboratory, Ohio Department of Agriculture, Reynoldsburg, OH, 43068, USA.
Arch Virol. 2016 Nov;161(11):3285-9. doi: 10.1007/s00705-016-2999-0. Epub 2016 Aug 8.
A previously unidentified chicken parvovirus (ChPV) strain, associated with runting-stunting syndrome (RSS), is now endemic among chickens in China. To explore the genetic diversity of ChPV strains, we determined the first complete genome sequence of a novel ChPV isolate (GX-CH-PV-7) identified in chickens in Guang Xi, China, and showed moderate genome sequence similarity to reference strains. Analysis showed that the viral genome sequence is 86.4 %-93.9 % identical to those of other ChPVs. Genetic and phylogenetic analyses showed that this newly emergent GX-CH-PV-7 is closely related to Gallus gallus enteric parvovirus isolate ChPV 798 from the USA, indicating that they may share a common ancestor. The complete DNA sequence is 4612 bp long with an A+T content of 56.66 %. We determined the first complete genome sequence of a previously unidentified ChPV strain to elucidate its origin and evolutionary status.
一种先前未被鉴定出的与矮小综合征（RSS）相关的鸡细小病毒（ChPV）毒株，目前在中国鸡群中呈地方性流行。为了探究ChPV毒株的遗传多样性，我们测定了在中国广西鸡群中鉴定出的一种新型ChPV分离株（GX-CH-PV-7）的首个完整基因组序列，该序列与参考毒株的基因组序列相似度适中。分析表明，该病毒基因组序列与其他ChPV的序列一致性为86.4% - 93.9%。遗传和系统发育分析表明，这种新出现的GX-CH-PV-7与来自美国的家鸡肠道细小病毒分离株ChPV 798密切相关，这表明它们可能有共同的祖先。完整的DNA序列长4612 bp，A+T含量为56.66%。我们测定了一种先前未被鉴定出的ChPV毒株的首个完整基因组序列，以阐明其起源和进化地位。
