Menezes de Oliveira Alane Cabral, Albuquerque Santos Arianne, Rodrigues Bezerra Alexandra, Machado Tavares Myrian Cicyanne, Rocha de Barros Amanda Maria, Costa Ferreira Raphaela
Faculdade de Nutrição, Universidade Federal de Alagoas, Maceió, AL, Brasil.
Hospital Universitário Professor Alberto Antunes, Universidade Federal de Alagoas (HUPPA/UFAL), Maceió, AL, Brasil.
Rev Port Cardiol. 2016 Sep;35(9):469-76. doi: 10.1016/j.repc.2016.03.005. Epub 2016 Aug 5.
Oxidative stress appears to play a critical role in the pathogenesis of preeclampsia. Evidence suggests that adequate intake of antioxidants can modulate this condition. The objective of this study was to assess the intake of antioxidant nutrients and coefficients of variation in pregnant women with preeclampsia.
In a cross-sectional study in the public health network of the city of Maceió, Brazil, a dietary survey was performed consisting of 24-hour food recalls, with subsequent adjustment of nutrients using the estimated average requirement as the cutoff point, and a questionnaire on frequency of consumption of antioxidants.
We studied 90 pregnant women with preeclampsia (PWP) and 90 pregnant women without preeclampsia (PWoP) with mean ages of 25.8±6.7 years and 24.1±6.2 years (p=0.519), respectively. A low mean intake of antioxidants (vitamin A, selenium, zinc and copper) was observed in both PWP and PWoP, although intakes of vitamin A (p=0.045) and selenium (p=0.008) were higher in PWoP. In addition, we observed high coefficients of variation in nutrient intakes in both groups, which were higher for vitamin C (p<0.001), vitamin A (p=0.006) and copper (p=0.005) in PWP.
Consumption of antioxidant nutrients by pregnant women with preeclampsia is inadequate, with considerable daily variations in intake, which points to a need for nutrition education strategies aimed at improving intakes, because diet is without doubt a key factor in the modulation of oxidative stress caused by preeclampsia.
氧化应激似乎在子痫前期的发病机制中起关键作用。有证据表明，充足摄入抗氧化剂可调节这种状况。本研究的目的是评估子痫前期孕妇抗氧化营养素的摄入量及变异系数。
在巴西马塞约市公共卫生网络的一项横断面研究中，进行了一项饮食调查，包括24小时食物回顾法，随后以估计平均需求量为临界点对营养素进行调整，并进行了一份关于抗氧化剂消费频率的问卷调查。
我们研究了90名单纯收缩期高血压孕妇（PWP）和90名非子痫前期孕妇（PWoP），平均年龄分别为25.8±6.7岁和24.1±6.2岁（p=0.519）。在PWP和PWoP中均观察到抗氧化剂（维生素A、硒、锌和铜）的平均摄入量较低，尽管PWoP中维生素A（p=0.045）和硒（p=0.008）的摄入量较高。此外，我们观察到两组营养素摄入量的变异系数都很高，PWP中维生素C（p<0.001）、维生素A（p=0.006）和铜（p=0.005）的变异系数更高。
子痫前期孕妇的抗氧化营养素摄入量不足，且每日摄入量存在相当大的差异，这表明需要采取营养教育策略来提高摄入量，因为饮食无疑是调节子痫前期所致氧化应激的关键因素。
