Haddock Ellen S, Cheng Carol E, Bradley John S, Hsu Christopher H, Zhao Hui, Davidson Whitni B, Barrio Victoria R
School of Medicine, University of California, San Diego, San Diego, CA, USA.
Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Pediatr Dermatol. 2017 Nov;34(6):e337-e340. doi: 10.1111/pde.13259. Epub 2017 Sep 21.
Orf is a zoonotic parapoxvirus typically transmitted to humans by a bite from goats or sheep. We present an unusual case of multiple orf lesions on the fingers of a 13-month-old child who was bitten by a goat and subsequently developed progressive swelling, blistering, and necrotic papulonodules of the hand followed by an additional diffuse, pruritic, papular rash. A primary diagnosis of orf infection was confirmed using real-time polymerase chain reaction, and the diffuse eruption was clinically consistent with an id reaction. Extensive necrosis and papular id reaction associated with orf rarely have been described.
羊痘是一种人畜共患的副痘病毒,通常通过山羊或绵羊的咬伤传播给人类。我们报告了一例不寻常的病例,一名13个月大的儿童手指上出现多处羊痘损伤,该儿童被山羊咬伤,随后手部出现进行性肿胀、水疱和坏死性丘疹结节,接着又出现弥漫性、瘙痒性丘疹皮疹。通过实时聚合酶链反应确诊为羊痘感染,弥漫性皮疹在临床上与自体敏感性反应一致。与羊痘相关的广泛坏死和丘疹性自体敏感性反应鲜有报道。