Guo Jin, Shi Yingfei, Xu Chengbao, Zhong Rugang, Zhang Feng, Niu Bo, Wang Jianhua, Zhang Ting
Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing 100020, China.
Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing 100020, China; Beijing Key Laboratory of Environmental & Viral Oncology, College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China.
Data Brief. 2016 Jul 19;8:1040-3. doi: 10.1016/j.dib.2016.07.024. eCollection 2016 Sep.
Myo-inositol (MI) is one of the stereoisomers of hexahydroxycyclohexane, which plays an important role in intracellular signal pathway. Derivatization is an indispensable step in both external and internal standard method during the chromatography-mass spectrometer (GC-MS) detection, as MI can't be ionized directly. It is valuable to optimize the derivative process and the detection volume for clinical detection. This article contains optimization data related to research publication "Quantification of plasma myo-inositol using gas chromatography-mass spectrometry" [1]. Here we introduce the data on the optimized derivatization volume, temperature, duration and the detection volume.
肌醇（MI）是六羟基环己烷的立体异构体之一，在细胞内信号通路中发挥重要作用。在色谱 - 质谱联用仪（GC-MS）检测过程中，衍生化是外标法和内标法中不可或缺的步骤，因为肌醇不能直接电离。优化衍生化过程和检测量对于临床检测具有重要价值。本文包含与研究论文《使用气相色谱 - 质谱法测定血浆肌醇》[1]相关的优化数据。在此，我们介绍关于优化衍生化体积、温度、持续时间和检测量的数据。
