Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St., CPZN 5206, Boston, MA, 02114, USA.
Division of Interventional Radiology, Massachusetts General Hospital, 55 Fruit St., Boston, MA, 02114, USA.
Adv Mater. 2016 Oct;28(39):8675-8680. doi: 10.1002/adma.201602606. Epub 2016 Aug 12.
A novel metallo-bioadhesive to be used as tissue sealant in minimally invasive procedures is reported. Metal complexation can be used to render gelatin derivatives adhesive, which occurs in minutes, is efficient, and fully biodegradable within weeks.
报道了一种新型的金属生物黏附剂,可用作微创程序中的组织密封剂。金属络合作用可使明胶衍生物具有黏附性,这种黏附作用在数分钟内发生,高效且完全可在数周内生物降解。