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[老年人主动脉瓣置换术]

[Aortic valve replacement in the elderly].

作者信息

Vogt F, Wicklein S, Singler K, Pfeiffer S, Fischlein T, Schwab J, Pauschinger M, Jessl J

机构信息

Klinik für Herzchirurgie, Klinikum Nürnberg, Paracelsus Medizinische Privatuniversität, Breslauer Str. 201, 90471, Nürnberg, Deutschland.

Medizinische Klinik 2, Schwerpunkt Geriatrie, Klinikum Nürnberg, Paracelsus Medizinische Privatuniversität, Nürnberg, Deutschland.

出版信息

Z Gerontol Geriatr. 2016 Oct;49(7):639-656. doi: 10.1007/s00391-016-1112-3. Epub 2016 Aug 12.

DOI:10.1007/s00391-016-1112-3
PMID:27518151
Abstract

The treatment of severe symptomatic aortic valve stenosis by conventional aortic valve replacement (AVR) or by transcatheter aortic valve implantation (TAVI) has a good perinterventional prognosis even for patients of advanced age. Having a heart team select the best management strategies based on current guidelines for each individual patient is essential for success. Especially in elderly and increasingly multimorbid patients with sometimes severe preconditions, the detection of functional deficits is relevant not only for the mortality but also for perioperative and postoperative complications as well as the functional outcome. Various methods of geriatric assessment are important supplements to standard risk scores. The aim is to implement targeted interventions to minimize the risk factors and to improve the prognosis for elderly patients. The aim of this article is to provide an overview of the current therapy options for aortic valve replacement and to summarize current aspects of treatment options for elderly patients.

摘要

对于重度有症状的主动脉瓣狭窄患者,采用传统主动脉瓣置换术(AVR)或经导管主动脉瓣植入术(TAVI)治疗,即使对于高龄患者,围介入期预后也较好。由心脏团队根据当前指南为每位患者选择最佳管理策略是成功的关键。特别是在老年且合并症日益增多、有时存在严重基础疾病的患者中,功能缺陷的检测不仅与死亡率相关,还与围手术期和术后并发症以及功能结局相关。各种老年评估方法是标准风险评分的重要补充。目的是实施有针对性的干预措施,以最小化风险因素并改善老年患者的预后。本文旨在概述当前主动脉瓣置换的治疗选择,并总结老年患者治疗选择的当前方面。

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1
[Aortic valve replacement in the elderly].[老年人主动脉瓣置换术]
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本文引用的文献

1
Incidence, Predictive Factors, and Effect of Delirium After Transcatheter Aortic Valve Replacement.经导管主动脉瓣置换术后谵妄的发生率、预测因素及影响。
JACC Cardiovasc Interv. 2016 Jan 25;9(2):160-8. doi: 10.1016/j.jcin.2015.09.037.
2
Delirium after surgical and transcatheter aortic valve replacement is associated with increased mortality.外科手术和经导管主动脉瓣置换术后的谵妄与死亡率增加相关。
J Thorac Cardiovasc Surg. 2016 Mar;151(3):815-823.e2. doi: 10.1016/j.jtcvs.2015.10.114. Epub 2015 Nov 11.
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经导管主动脉瓣置换术的可及性对临床实践的影响。
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Frailty scoring in transcatheter aortic valve replacement patients.经导管主动脉瓣置换术患者的衰弱评分
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5
Mortality Predictors in Patients Referred for but Not Undergoing Transcatheter Aortic Valve Replacement.接受经导管主动脉瓣置换术评估但未进行该手术患者的死亡预测因素
Am J Cardiol. 2015 Sep 15;116(6):919-24. doi: 10.1016/j.amjcard.2015.06.014. Epub 2015 Jun 25.
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[Analgesics in geriatric patients. Adverse side effects and interactions].老年患者的镇痛药。副作用及相互作用
Z Gerontol Geriatr. 2015 Jul;48(5):483-92; quiz 493. doi: 10.1007/s00391-015-0922-z.
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Aortic valve surgery in octogenarians: the simpler, the better?
Ann Thorac Surg. 2015 Feb;99(2):746. doi: 10.1016/j.athoracsur.2014.07.022.
8
Cardiac rehabilitation and mid-term follow-up after transcatheter aortic valve implantation.经导管主动脉瓣植入术后的心脏康复和中期随访。
J Geriatr Cardiol. 2014 Dec;11(4):279-85. doi: 10.11909/j.issn.1671-5411.2014.04.001.
9
Update on transcatheter aortic valve replacement.经导管主动脉瓣置换术的最新进展
Trends Cardiovasc Med. 2015 Feb;25(2):154-61. doi: 10.1016/j.tcm.2014.10.001. Epub 2014 Oct 13.
10
Predictors of poor outcomes after transcatheter aortic valve replacement: results from the PARTNER (Placement of Aortic Transcatheter Valve) trial.经导管主动脉瓣置换术后不良结局的预测因素:PARTNER(主动脉经导管瓣膜置换术)试验结果。
Circulation. 2014 Jun 24;129(25):2682-90. doi: 10.1161/CIRCULATIONAHA.113.007477. Epub 2014 May 23.