Terui T, Tagami H
Department of Dermatology, Tohoku University School of Medicine, Sendai, Japan.
Contact Dermatitis. 1989 Apr;20(4):260-4. doi: 10.1111/j.1600-0536.1989.tb03142.x.
We report a 46-year-old patient with an eczematous eruption on sun-exposed areas which we believe was caused by carbamazepine intake. Oral provocation with the drug produced papulo-vesicular eruptions that were greatly potentiated by long-wave ultraviolet irradiation. Positive reactions to carbamazepine were elicited by patch and photopatch tests and by lymphocyte stimulation tests 6 months after cessation of the intake of carbamazepine.
我们报告了一名46岁的患者,其暴露于阳光下的部位出现湿疹样皮疹,我们认为这是由服用卡马西平引起的。对该药物进行口服激发试验产生了丘疹水疱性皮疹,长波紫外线照射可使其显著加重。在停止服用卡马西平6个月后,通过斑贴试验、光斑贴试验和淋巴细胞刺激试验均得出了对卡马西平的阳性反应。