Liao Xiaolei, Zhao Juanjuan, Jiao Cheng, Lei Lei, Qiang Yan, Cui Qiang
College of Computer Science and Technology, Taiyuan University of Technology, Taiyuan, 030024, China.
PET/CT center of Shanxi coal Central Hospital, Taiyuan, Shanxi, 030024, China.
PLoS One. 2016 Aug 17;11(8):e0160556. doi: 10.1371/journal.pone.0160556. eCollection 2016.
Lung parenchyma segmentation is often performed as an important pre-processing step in the computer-aided diagnosis of lung nodules based on CT image sequences. However, existing lung parenchyma image segmentation methods cannot fully segment all lung parenchyma images and have a slow processing speed, particularly for images in the top and bottom of the lung and the images that contain lung nodules.
Our proposed method first uses the position of the lung parenchyma image features to obtain lung parenchyma ROI image sequences. A gradient and sequential linear iterative clustering algorithm (GSLIC) for sequence image segmentation is then proposed to segment the ROI image sequences and obtain superpixel samples. The SGNF, which is optimized by a genetic algorithm (GA), is then utilized for superpixel clustering. Finally, the grey and geometric features of the superpixel samples are used to identify and segment all of the lung parenchyma image sequences.
Our proposed method achieves higher segmentation precision and greater accuracy in less time. It has an average processing time of 42.21 seconds for each dataset and an average volume pixel overlap ratio of 92.22 ± 4.02% for four types of lung parenchyma image sequences.
肺实质分割通常作为基于CT图像序列的肺结节计算机辅助诊断中的重要预处理步骤。然而,现有的肺实质图像分割方法无法完全分割所有肺实质图像,且处理速度较慢,特别是对于肺顶部和底部的图像以及包含肺结节的图像。
我们提出的方法首先利用肺实质图像特征的位置来获取肺实质ROI图像序列。然后提出一种用于序列图像分割的梯度和顺序线性迭代聚类算法(GSLIC)来分割ROI图像序列并获得超像素样本。接着利用通过遗传算法(GA)优化的SGNF进行超像素聚类。最后,使用超像素样本的灰度和几何特征来识别和分割所有肺实质图像序列。
我们提出的方法在更短的时间内实现了更高的分割精度和更高的准确性。对于每个数据集,其平均处理时间为42.21秒,对于四种类型的肺实质图像序列,平均体积像素重叠率为92.22±4.02%。