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孕产妇严重发病与健康相关生活质量的即时和长期关系:一项前瞻性双队列比较研究。

Immediate and long-term relationship between severe maternal morbidity and health-related quality of life: a prospective double cohort comparison study.

作者信息

Norhayati Mohd Noor, Nik Hazlina Nik Hussain, Aniza Abd Aziz

机构信息

Department of Family Medicine, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, 16150, Kota Bharu, Kelantan, Malaysia.

Women's Health Development Unit, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, 16150, Kota Bharu, Kelantan, Malaysia.

出版信息

BMC Public Health. 2016 Aug 18;16(1):818. doi: 10.1186/s12889-016-3524-9.

Abstract

BACKGROUND

Given the growing interest in severe maternal morbidity (SMM), the need to assess its effects on quality of life is pressing. The objective of this study was to compare the quality of life scores between women with and without SMM at 1-month and 6-month postpartum in Kelantan, Malaysia.

METHODS

A prospective double cohort study design was applied at two tertiary referral hospitals over a 6-month period. The study population included all postpartum women who delivered in 2014. Postpartum women with and without SMM were selected as the exposed and non-exposed groups, respectively. For each exposed case identified, a non-exposed case with a similar mode of delivery was selected. The main outcome measures used were scores from the Short Form-12 Health Survey (SF-12).

RESULTS

The study measured 145 exposed and 187 non-exposed women. The group-time interaction of the repeated measure analysis of variance (RM ANOVA) showed no significant difference in the mean overall SF-12 physical component summary score changes (P = 0.534) between women with and without SMM. Similarly, the group-time interaction of the RM ANOVA showed no significant difference in the mean overall SF-12 mental component summary score changes (P = 0.674) between women with and without SMM. However, women with SMM scored significantly lower on a general health perceptions subscale at 1-month (P = 0.031), role limitations due to physical health subscale at 6-month (P = 0.019), vitality subscale at 1-month (P = 0.007) and 6-month (P = 0.008), and role limitations due to emotional problems subscales at 6-month (P = 0.008).

CONCLUSIONS

Women with severe maternal morbidity demonstrated comparable quality of life during the 6-month postpartum period compared to women without severe maternal morbidity.

摘要

背景

鉴于对严重孕产妇发病(SMM)的关注度日益增加,评估其对生活质量的影响迫在眉睫。本研究的目的是比较马来西亚吉兰丹州产后1个月和6个月时患有和未患有SMM的女性的生活质量得分。

方法

在两家三级转诊医院进行了为期6个月的前瞻性双队列研究设计。研究人群包括2014年分娩的所有产后女性。患有和未患有SMM的产后女性分别被选为暴露组和非暴露组。对于每例确定的暴露病例,选择一名分娩方式相似的非暴露病例。主要结局指标采用简短健康调查问卷(SF-12)的得分。

结果

该研究对145名暴露组女性和187名非暴露组女性进行了测量。重复测量方差分析(RM ANOVA)的组间时间交互作用显示,患有和未患有SMM的女性在SF-12身体成分综合平均得分变化方面无显著差异(P = 0.534)。同样,RM ANOVA的组间时间交互作用显示,患有和未患有SMM的女性在SF-12心理成分综合平均得分变化方面无显著差异(P = 0.674)。然而,患有SMM的女性在产后1个月的一般健康感知子量表得分显著较低(P = 0.031),产后6个月的身体健康所致角色限制子量表得分显著较低(P = 0.019),产后1个月(P = 0.007)和6个月(P = 0.008)的活力子量表得分显著较低,产后6个月的情绪问题所致角色限制子量表得分显著较低(P = 0.008)。

结论

与未患有严重孕产妇发病的女性相比,患有严重孕产妇发病的女性在产后6个月期间的生活质量相当。

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