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亚洲的气传过敏原致敏和过敏性疾病表型。

Aeroallergen sensitization and allergic disease phenotypes in Asia.

机构信息

Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore and Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore.

出版信息

Asian Pac J Allergy Immunol. 2016 Sep;34(3):181-189. doi: 10.12932/AP0770.

DOI:10.12932/AP0770
PMID:27543739
Abstract

Allergic diseases are on the rise in Asia. Aeroallergen exposure is a strong risk factor for sensitization, development and severity of atopic diseases, especially in the Asian paediatric population. Geographical and seasonal variations in aeroallergen sensitization are seen even within Asian countries and changes in aeroallergen sensitization patterns have been observed over time. Some possible reasons include climate change as well as rapid urbanization and improved sanitation which follow socioeconomic development. House dust mite allergy is present in up to 90% of Asian atopic patients, far exceeding that which is seen in Western populations which report prevalences of only 50% to 70%. Pollen and animal dander affect less than 10% of Asian patients as compared to 40-70% of individuals with asthma and allergic rhinitis living in the West, a burden almost equivalent to the dust mite burden in those regions. There is thus a pressing need for preventive measures to reduce dust mite sensitization in Asian children today.

摘要

亚洲的过敏性疾病正在呈上升趋势。气传过敏原暴露是致敏、特应性疾病发展和严重程度的一个重要危险因素,特别是在亚洲儿科人群中。即使在亚洲国家内部,气传过敏原致敏也存在地理和季节性差异,而且气传过敏原致敏模式随时间也发生了变化。一些可能的原因包括气候变化以及紧随社会经济发展的快速城市化和卫生条件改善。屋尘螨过敏在多达 90%的亚洲特应性患者中存在,远远超过西方人群的 50%至 70%的报告患病率。花粉和动物皮屑影响不到 10%的亚洲患者,而生活在西方的哮喘和过敏性鼻炎患者中,有 40%至 70%的患者受到影响,这一负担几乎与这些地区的尘螨负担相当。因此,现在迫切需要采取预防措施来减少亚洲儿童对尘螨的致敏。

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