Wang Mengmeng, Wang Sheng, Zhang Xu, Xia Qing, Cai Guoqi, Yang Xiao, Li Xiaona, Wang Li, Xin Lihong, Xu Shengqian, Xu Jianhua, Shuai Zongwen, Pan Faming
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, Anhui, 230032, China.
Department of Rheumatism and Immunity, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, China.
Health Qual Life Outcomes. 2016 Aug 22;14(1):118. doi: 10.1186/s12955-016-0522-7.
To examine the subjective well-being (SWB) in patients with ankylosing spondylitis (AS) compared with the healthy controls, and to explore the associations between SWB and demographic characteristics, disease-specific variables in AS patients.
SWB was assessed with General Well-Being Schedule (GWBS) in 200 AS patients and 210 healthy controls. Comparisons among subgroups were performed to investigate how certain aspects operate as favorable or adverse factors in influencing SWB in the patients with AS.
Both men and women with AS reported significantly impaired SWB on all scales of the GWBS except for the Control (O) scale. The results revealed that better sleep, lower disease activity and more family care predicted higher SWB. In AS patients, positive attitude towards therapy prospect was significantly associated with higher SWB. Therapy prospect refers to the hope of patients about the disease treatment.
Compared with general population, SWB might be affected by the onset of AS. There are significant associations between SWB and sleep quality, BASDAI, APGAR, therapy prospect.
为了研究强直性脊柱炎（AS）患者与健康对照者的主观幸福感（SWB），并探讨AS患者中SWB与人口统计学特征、疾病特异性变量之间的关联。
采用总体幸福感量表（GWBS）对200例AS患者和210名健康对照者的SWB进行评估。对亚组进行比较，以研究某些方面如何作为影响AS患者SWB的有利或不利因素。
除控制（O）量表外，AS患者无论男女在GWBS的所有量表上均报告SWB显著受损。结果显示，更好的睡眠、更低的疾病活动度和更多的家庭关怀预示着更高的SWB。在AS患者中，对治疗前景的积极态度与更高的SWB显著相关。治疗前景是指患者对疾病治疗的希望。
与一般人群相比，SWB可能受AS发病的影响。SWB与睡眠质量、BASDAI、APGAR、治疗前景之间存在显著关联。
