Wu Meiyan, Long Zhu, Xiao Huining, Dong Cuihua
Key Laboratory of Eco-textiles, Ministry of Education, Jiangnan University, Wuxi 214122, China; Key Laboratory of Pulp and Paper Science & Technology of Ministry of Education of China, Qilu University of Technology, Jinan 250353, China; Department of Chemical Engineering, University of New Brunswick, Fredericton E3B 5A3, Canada.
Key Laboratory of Eco-textiles, Ministry of Education, Jiangnan University, Wuxi 214122, China; Key Laboratory of Pulp and Paper Science & Technology of Ministry of Education of China, Qilu University of Technology, Jinan 250353, China.
Carbohydr Res. 2016 Nov 3;434:27-32. doi: 10.1016/j.carres.2016.08.002. Epub 2016 Aug 3.
N,N,N-trimethyl chitosan (TMC) is a quaternized chitosan derivative with excellent solubility in aqueous solutions. It has been extensively studied as an absorption enhancer, antibacterial agent and gene vector due to its ability to form complexes with anionic gels or macromoleculars. However, the research which describes the process of TMC preparation and its new applications has not been fully reviewed. In this paper, recent progress regarding different TMC preparation methods and its characterization and application in different fields is presented. Key findings are compared and summarized and some topics for further study are suggested.
N,N,N-三甲基壳聚糖（TMC）是一种季铵化壳聚糖衍生物，在水溶液中具有优异的溶解性。由于它能够与阴离子凝胶或大分子形成复合物，因此作为吸收增强剂、抗菌剂和基因载体受到了广泛研究。然而，关于TMC制备过程及其新应用的研究尚未得到充分综述。本文介绍了不同TMC制备方法及其表征和在不同领域应用的最新进展。对关键发现进行了比较和总结，并提出了一些有待进一步研究的课题。
