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壳聚糖及其衍生物:制备方法与抗菌性能

Chitosan and Its Derivatives: Preparation and Antibacterial Properties.

作者信息

Egorov Anton R, Kirichuk Anatoly A, Rubanik Vasili V, Rubanik Vasili V, Tskhovrebov Alexander G, Kritchenkov Andreii S

机构信息

Department of Human Ecology and Biolementology, RUDN University, 6 Miklukho-Maklaya St., 117198 Moscow, Russia.

Institute of Technical Acoustics NAS of Belarus, Ludnikova Prosp. 13, 210009 Vitebsk, Belarus.

出版信息

Materials (Basel). 2023 Sep 5;16(18):6076. doi: 10.3390/ma16186076.

DOI:10.3390/ma16186076
PMID:37763353
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10532898/
Abstract

This comprehensive review illuminates the various methods of chitosan extraction, its antibacterial properties, and its multifarious applications in diverse sectors. We delve into chemical, physical, biological, hybrid, and green extraction techniques, each of which presents unique advantages and disadvantages. The choice of method is dictated by multiple variables, including the desired properties of chitosan, resource availability, cost, and environmental footprint. We explore the intricate relationship between chitosan's antibacterial activity and its properties, such as cationic density, molecular weight, water solubility, and pH. Furthermore, we spotlight the burgeoning applications of chitosan-based materials like films, nanoparticles, nonwoven materials, and hydrogels across the food, biomedical, and agricultural sectors. The review concludes by highlighting the promising future of chitosan, underpinned by technological advancements and growing sustainability consciousness. However, the critical challenges of optimizing chitosan's production for sustainability and efficiency remain to be tackled.

摘要

这篇综述全面阐述了壳聚糖的各种提取方法、抗菌特性及其在不同领域的多种应用。我们深入探讨了化学、物理、生物、混合和绿色提取技术,每种技术都有其独特的优缺点。方法的选择取决于多个变量,包括壳聚糖所需的特性、资源可用性、成本和环境影响。我们探究了壳聚糖的抗菌活性与其阳离子密度、分子量、水溶性和pH值等特性之间的复杂关系。此外,我们重点介绍了基于壳聚糖的材料,如薄膜、纳米颗粒、非织造材料和水凝胶在食品、生物医学和农业领域的新兴应用。综述最后强调了壳聚糖充满希望的未来,这得益于技术进步和日益增强的可持续发展意识。然而,优化壳聚糖生产以实现可持续性和效率的关键挑战仍有待解决。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fbb/10532898/97a9712ba4ab/materials-16-06076-sch003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fbb/10532898/3ada028228f5/materials-16-06076-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fbb/10532898/9cc2f37d9e0d/materials-16-06076-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fbb/10532898/2f22eb2b7fb6/materials-16-06076-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fbb/10532898/46c6efcdaf05/materials-16-06076-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fbb/10532898/572f20e1b48a/materials-16-06076-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fbb/10532898/97a9712ba4ab/materials-16-06076-sch003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fbb/10532898/3ada028228f5/materials-16-06076-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fbb/10532898/9cc2f37d9e0d/materials-16-06076-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fbb/10532898/2f22eb2b7fb6/materials-16-06076-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fbb/10532898/46c6efcdaf05/materials-16-06076-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fbb/10532898/572f20e1b48a/materials-16-06076-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fbb/10532898/97a9712ba4ab/materials-16-06076-sch003.jpg

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