运动医学中膳食补充剂的潜在有害影响。

Potential harmful effects of dietary supplements in sports medicine.

作者信息

Deldicque Louise, Francaux Marc

机构信息

Institute of Neuroscience, Université catholique de Louvain, Louvain-la-Neuve, Belgium.

出版信息

Curr Opin Clin Nutr Metab Care. 2016 Nov;19(6):439-445. doi: 10.1097/MCO.0000000000000321.

Abstract

PURPOSE OF REVIEW

The purpose of this article is to collect the most recent data regarding the safety of well-known or emerging dietary supplements used by athletes.

RECENT FINDINGS

From January 2014 to April 2016, about 30 articles have been published in the field. New data show that 90% of sports supplements contain trace of estrogenic endocrine disruptors, with 25% of them having a higher estrogenic activity than acceptable. About 50% of the supplements are contaminated by melamine, a source of nonprotein nitrogen. Additional data accumulate toward the safety of nitrate ingestion. In the last 2 years, the safety of emerging supplements such as higenamine, potentially interesting to lose weight, creatine nitrate and guanidinoacetic acid has been evaluated but still needs further investigation.

SUMMARY

The consumption of over-the-counter supplements is very popular in athletes. Although most supplements may be considered as safe when taking at the recommended doses, athletes should be aware of the potential risks linked to the consumption of supplements. In addition to the risks linked to overdosage and cross-effects when combining different supplements at the same time, inadvertent or deliberate contamination with stimulants, estrogenic compounds, diuretics or anabolic agents may occur.

摘要

综述目的

本文旨在收集有关运动员使用的知名或新兴膳食补充剂安全性的最新数据。

最新发现

2014年1月至2016年4月期间,该领域已发表约30篇文章。新数据显示,90%的运动补充剂含有微量雌激素内分泌干扰物,其中25%的雌激素活性高于可接受水平。约50%的补充剂被三聚氰胺污染,三聚氰胺是非蛋白氮的来源。关于摄入硝酸盐的安全性,有更多数据积累。在过去两年中,已对诸如去甲乌药碱(可能对减肥有潜在益处)、硝酸肌酸和胍基乙酸等新兴补充剂的安全性进行了评估,但仍需进一步研究。

总结

非处方补充剂在运动员中使用非常普遍。虽然大多数补充剂按推荐剂量服用时可能被认为是安全的,但运动员应意识到与补充剂消费相关的潜在风险。除了与过量服用以及同时服用不同补充剂时的交叉作用相关的风险外,还可能发生无意或故意被兴奋剂、雌激素化合物、利尿剂或合成代谢剂污染的情况。

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