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基于经验得出的饮食模式与高血压患病可能性:一项荟萃分析。

Empirically Derived Dietary Patterns and Hypertension Likelihood: A Meta-Analysis.

作者信息

Wang Cui-Jiang, Shen You-Xia, Liu Yun

机构信息

Division of Foot and Ankle Surgery, Linyi People's Hospital, Linyi, Shandong, China.

出版信息

Kidney Blood Press Res. 2016;41(5):570-581. doi: 10.1159/000443456. Epub 2016 Aug 24.

Abstract

BACKGROUND/AIMS: Dietary patterns, which represent whole-diet and a complex integration of food and nutrient, have been reported to play an important role in the development of hypertension. However, the results have yielded conflicting findings. Herein, we performed this meta-analysis to evaluate the associations between different dietary patterns and the likelihood of hypertension.

METHODS

MEDLINE and EBSCO were searched to identify relevant articles published until the end of March 2016. A random-effects model was used to account for possible heterogeneity between studies.A total of twenty-seven studies met the inclusion criteria and were included in this meta-analysis.

RESULTS

There was evidence of a decreased likelihood for hypertension in the highest compared with the lowest categories of healthy pattern (odds ratio (OR)=0.81; 95% confidence interval(CI): 0.67-0.97; P=0.02). An increased likelihood of hypertension was shown for the highest compared with the lowest category of heavy drinking pattern (OR=1.62; 95% CI: 1.16-2.26; P=0.004), whereas no statistically significant association with western-style and light-moderate drinking pattern were observed(OR=1.04, 95% CI: 0.83-1.31; OR=1.20, 95% CI:0.94- 1.53; P>0.05).

CONCLUSIONS

Our results of this systematic review and meta-analysis suggest that dietary pattern may be associated with the likelihood of hypertension.

摘要

背景/目的:饮食模式代表了整体饮食以及食物和营养素的复杂组合,据报道其在高血压的发生发展中起着重要作用。然而,研究结果却相互矛盾。在此,我们进行了这项荟萃分析,以评估不同饮食模式与高血压发生可能性之间的关联。

方法

检索了MEDLINE和EBSCO,以确定截至2016年3月底发表的相关文章。采用随机效应模型来考虑研究之间可能存在的异质性。共有27项研究符合纳入标准并被纳入本荟萃分析。

结果

有证据表明,与健康模式最低类别相比,最高类别者患高血压的可能性降低(优势比(OR)=0.81;95%置信区间(CI):0.67 - 0.97;P = 0.02)。与重度饮酒模式最低类别相比,最高类别者患高血压的可能性增加(OR = 1.62;95% CI:1.16 - 2.26;P = 0.004),而未观察到与西式和轻度 - 中度饮酒模式存在统计学显著关联(OR = 1.04,95% CI:0.83 - 1.31;OR = 1.20,95% CI:0.94 - 1.53;P > 0.05)。

结论

我们这项系统评价和荟萃分析的结果表明,饮食模式可能与高血压的发生可能性相关。

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