患有唐氏综合征的巴西成年人的血压水平和体重指数。
Blood pressure levels and body mass index in Brazilian adults with Down syndrome.
作者信息
Pucci Felipe, Machado Guilherme, Solera Edcarlo, Cenovicz Fernanda, Arruda Christian, Braga Chiu, Nisihara Renato
机构信息
MD. Attending Physician, Department of Medicine, Universidade Positivo (UP), Curitiba, PR, Brazil.
Undergraduate Student, Department of Medicine, Universidade Positivo (UP), Curitiba, PR, Brazil.
出版信息
Sao Paulo Med J. 2016 Jul-Aug;134(4):330-4. doi: 10.1590/1516-3180.2016.0057180316.
CONTEXT AND OBJECTIVE
Increased life expectancy among people with Down syndrome (DS) has introduced new environmental factors that may affect blood pressure (BP) and/or lead to obesity in this population. The aim here was to investigate BP levels and body mass index (BMI) in adults with DS, correlating these data with the patients' sex and age.
DESIGN AND SETTING
Analytical cross-sectional observational study conducted in special schools in Curitiba (PR), Brazil.
METHODS
97 adult patients were included. BP was measured in accordance with the established guidelines. BMI was calculated by dividing the weight by the height squared (kg/m2).
RESULTS
Sex had no influence on BMI; nor did systolic BP (SBP) or diastolic BP (DBP). The age range was from 18 to 56 years. No correlation was observed between increasing age and greater BMI or BP. Eighty-six individuals (88.7%) presented normal BP, eleven (11.3%) prehypertension and none hypertension. Twenty patients (20.4%) presented BP lower than 90 × 60 mmHg. BMI ranged from 18 to 48 kg/m2 (mean of 28.8 ± 3.92 kg/m2): 21.9% had normal weight; 40.7% were overweight; and 25.3% had obesity class I, 9.9% class II and 2.2% class III. Higher BMI was associated with significantly greater SBP and DBP (P = 0.0175 and P = 0.0015).
CONCLUSION
Sex and age did not influence SBP, DBP or BMI in Brazilian adults with DS. Higher BMI was associated with greater BP (both systolic and diastolic).
背景与目的
唐氏综合征（DS）患者预期寿命的增加引入了新的环境因素，这些因素可能影响该人群的血压（BP）和/或导致肥胖。本研究旨在调查成年DS患者的血压水平和体重指数（BMI），并将这些数据与患者的性别和年龄相关联。
设计与地点
在巴西库里蒂巴（PR）的特殊学校进行的分析性横断面观察研究。
方法
纳入97例成年患者。按照既定指南测量血压。BMI通过体重除以身高的平方（kg/m²）计算得出。
结果
性别对BMI没有影响；收缩压（SBP）或舒张压（DBP）也不受影响。年龄范围为18至56岁。未观察到年龄增长与更高的BMI或血压之间存在相关性。86人（88.7%）血压正常，11人（11.3%）为高血压前期，无人患高血压。20例患者（20.4%）血压低于90×60 mmHg。BMI范围为18至48 kg/m²（平均为28.8±3.92 kg/m²）：21.9%体重正常；40.7%超重；25.3%为I级肥胖，9.9%为II级肥胖，2.2%为III级肥胖。较高的BMI与显著更高的SBP和DBP相关（P = 0.0175和P = 0.0015）。
结论
在巴西成年DS患者中，性别和年龄不影响SBP、DBP或BMI。较高的BMI与更高的血压（收缩压和舒张压）相关。
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