Calderaro Débora Cerqueira, Ferreira Gilda Aparecida, Corrêa Jôice Dias, Mendonça Santuza Maria Souza, Silva Tarcília Aparecida, Costa Fernando Oliveira, Lúcio Teixeira Antônio
Rheumatology Service, Hospital das Clínicas, Universidade Federal de Minas Gerais, Rua Dona Nancy de Vasconcelos Gomes, 125/401, Sagrada Família, Belo Horizonte, Minas Gerais, CEP: 31030-071, Brazil.
Department of Locomotor System, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Clin Rheumatol. 2017 Mar;36(3):713-718. doi: 10.1007/s10067-016-3385-8. Epub 2016 Aug 24.
The aim of this study was to compare the frequency and severity of chronic periodontitis (CP) in systemic lupus erythematosus (SLE) patients with individuals without rheumatic diseases. Seventy-five patients with SLE were compared to 75 individuals without rheumatic diseases (control group) matched for age, educational level, and income. The activity of SLE was assessed with the Systemic Lupus Erythematosus Disease Activity Index 2000. Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index for Systemic Lupus Erythematosus evaluated SLE-related damage. Dental evaluation included measuring plaque index and parameters of periodontal disease (probing depth, clinical attachment level, and bleeding on probing). Fifty-one (68 %) SLE patients and 42 (56 %) control individuals had CP (p = 0.13). Periodontal status was similar in both groups. Considering only individuals with CP, SLE patients were younger than controls (40.7 ± 9.8 versus 46.14 ± 12.5 years of age, p = 0.02). CP was not associated with activity or therapeutics in SLE patients. Severity of periodontal parameters was similar in SLE patients and control subjects; however, CP occurred earlier in SLE patients.
本研究的目的是比较系统性红斑狼疮（SLE）患者与无风湿性疾病个体的慢性牙周炎（CP）的发生率和严重程度。将75例SLE患者与75例年龄、教育水平和收入相匹配的无风湿性疾病个体（对照组）进行比较。采用2000年系统性红斑狼疮疾病活动指数评估SLE的活动度。用系统性红斑狼疮国际协作临床中心/美国风湿病学会系统性红斑狼疮损伤指数评估SLE相关损伤。牙科评估包括测量菌斑指数和牙周疾病参数（探诊深度、临床附着水平和探诊出血）。51例（68%）SLE患者和42例（56%）对照个体患有CP（p = 0.13）。两组的牙周状况相似。仅考虑患有CP的个体，SLE患者比对照组年轻（年龄分别为40.7±9.8岁和46.14±12.5岁，p = 0.02）。CP与SLE患者的活动度或治疗方法无关。SLE患者和对照受试者的牙周参数严重程度相似；然而，CP在SLE患者中出现得更早。
