整体（细胞）小于其各部分之和。
The Whole (Cell) Is Less Than the Sum of Its Parts.
作者信息
Van Vranken Jonathan G, Rutter Jared
机构信息
Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84132, USA.
Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84132, USA; Howard Hughes Medical Institute, University of Utah School of Medicine, Salt Lake City, UT 84132, USA.
出版信息
Cell. 2016 Aug 25;166(5):1078-1079. doi: 10.1016/j.cell.2016.08.011.
Abstract
Despite advances in metabolite profiling, a full picture of the metabolic landscape of the cell has been limited by sub-cellular compartmentalization, which segregates distinct nutrient pools into membrane-bound organelles. Now, Chen et al. describe methods for overcoming this hurdle and provide a new quantitative picture of the mitochondrial metabolome.
摘要
尽管代谢物分析技术取得了进展，但细胞代谢景观的全貌一直受到亚细胞区室化的限制，亚细胞区室化将不同的营养库分隔到膜结合细胞器中。现在，陈等人描述了克服这一障碍的方法，并提供了线粒体代谢组的新定量图景。
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