Azamar-Jácome Amyra Ali, Azamar-Jácome Manuel Affid, Borjas-Aguilar Karla Leversia, Mendoza-Hernández David Alejandro, Huerta-López José Guadalupe
Secretaría de Salud, Instituto Nacional de Pediatría, Servicio de Alergia e Inmunología Clínica Pediátrica, Ciudad de México, México.
Rev Alerg Mex. 2017 Apr-Jun;64(2):142-152. doi: 10.29262/ram.v64i2.235.
Oral allergy syndrome (OAS) or pollen-fruit syndrome is a type of food allergy. Its characteristics and associated allergens vary according to the studied population. There are few studies in Mexico about this topic, none in children.
To describe clinical and epidemiological characteristics of OAS among children in Mexico.
A descriptive, observational, transversal and prospective study was conducted. We included every patient from 6 to 18 years old with diagnostic suspicion of OAS, in which complete clinical history, skin test to food and pollens, and oral food challenge were performed.
We found a prevalence of 5.3% (29 patients): 55% were males. Average age was 10 ± 3 years, and average number of food implicated were 6.8 ± 4.1. Apple, peach and banana, were the most frequent food associated, and sensitization to oak and European privet, the more prevalent pollens found in OAS.
OAS is a common type of food allergy, transient and mild in nature. In more than 90% of the cases is associated with allergic rhinitis and sensitization to pollens. In our population, profilins may be involved in its pathogenesis. However, more studies are required to prove this.
口腔过敏综合征（OAS）或花粉 - 水果综合征是一种食物过敏类型。其特征和相关过敏原因研究人群而异。在墨西哥，关于这个主题的研究很少，在儿童中则没有相关研究。
描述墨西哥儿童中口腔过敏综合征的临床和流行病学特征。
进行了一项描述性、观察性、横断面和前瞻性研究。我们纳入了每一位6至18岁疑似口腔过敏综合征诊断的患者，对其进行了完整的临床病史、食物和花粉皮肤试验以及口服食物激发试验。
我们发现患病率为5.3%（29例患者）：55%为男性。平均年龄为10±3岁，涉及的食物平均数量为6.8±4.1。苹果、桃子和香蕉是最常见的相关食物，对橡树和欧洲女贞的致敏是口腔过敏综合征中最常见的花粉致敏情况。
口腔过敏综合征是一种常见的食物过敏类型，本质上是短暂且轻微的。在超过90%的病例中，它与过敏性鼻炎和花粉致敏有关。在我们的研究人群中，肌动蛋白可能参与其发病机制。然而，需要更多研究来证实这一点。
