IncHI2质粒是负责oqxA B在沙门氏菌物种间传播的关键载体。
IncHI2 Plasmids Are the Key Vectors Responsible for oqxAB Transmission among Salmonella Species.
作者信息
Wong Marcus Ho-Yin, Chan Edward Wai-Chi, Xie Liqi, Li Ruichao, Chen Sheng
机构信息
Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, People's Republic of China.
State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
出版信息
Antimicrob Agents Chemother. 2016 Oct 21;60(11):6911-6915. doi: 10.1128/AAC.01555-16. Print 2016 Nov.
Abstract
This study reported and analyzed the complete sequences of two oqxAB-bearing IncHI2 plasmids harbored by a clinical Salmonella enterica serovar Typhimurium strain and an S Indiana strain of animal origin, respectively. In particular, pA3T recovered from S Indiana comprised the resistance determinants oqxAB, aac(6')Ib-cr, fosA3, and bla Further genetic screening of 63 oqxAB-positive Salmonella isolates revealed that the majority carried IncHI2 plasmids, confirming that such plasmids play a pivotal role in dissemination of oqxAB in Salmonella spp.
摘要
本研究报告并分析了分别由一株临床鼠伤寒沙门氏菌菌株和一株动物源印第安纳沙门氏菌菌株携带的两个携带oqxAB的IncHI2质粒的完整序列。特别地，从印第安纳沙门氏菌中回收的pA3T包含抗性决定簇oqxAB、aac(6')Ib-cr、fosA3和bla。对63株oqxAB阳性沙门氏菌分离株的进一步基因筛查显示，大多数携带IncHI2质粒，证实此类质粒在沙门氏菌属中oqxAB的传播中起关键作用。
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Sci Rep. 2016 May 4;6:25312. doi: 10.1038/srep25312.
2
Clinical Salmonella Typhimurium ST34 with metal tolerance genes and an IncHI2 plasmid carrying oqxAB-aac(6')-Ib-cr from Europe.
J Antimicrob Chemother. 2016 Mar;71(3):843-5. doi: 10.1093/jac/dkv409. Epub 2015 Dec 17.
3
Discrimination between native and Tn6010-associated oqxAB in Klebsiella spp., Raoultella spp., and other Enterobacteriaceae by using a two-step strategy.
Antimicrob Agents Chemother. 2015 Sep;59(9):5838-40. doi: 10.1128/AAC.00669-15. Epub 2015 Jun 29.
4
Evolution and dissemination of OqxAB-like efflux pumps, an emerging quinolone resistance determinant among members of Enterobacteriaceae.
Antimicrob Agents Chemother. 2015;59(6):3290-7. doi: 10.1128/AAC.00310-15. Epub 2015 Mar 23.
5
Differential contribution of AcrAB and OqxAB efflux pumps to multidrug resistance and virulence in Klebsiella pneumoniae.
J Antimicrob Chemother. 2015 Jan;70(1):81-8. doi: 10.1093/jac/dku340. Epub 2014 Sep 4.
6
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7
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PLoS One. 2013 Sep 9;8(9):e73947. doi: 10.1371/journal.pone.0073947. eCollection 2013.
8
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9
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10
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